Technologies

In this section it is possible to view, also through targeted research, the technologies inserted in the PROMO-TT Database. For further information on the technologies and to contact the CNR Research Teams who developed them, it is necessary to contact the Project Manager (see the references at the bottom of each record card).

Displaying results 31 - 45 of 56

# Record card
33
Description

Severe asthma or chronic obstructive pulmonary disease (COPD) are nowadays associated with a poor response to corticosteroids which led to the use of high-dose with consequent improved onset of side effects. The use of nanotechnologies can represent an innovative approach for the effective treatment of both asthma and COPD. The development of new nano-formulations involving the use of nanomaterials and specifically tailored to be inhaled offers numerous advantages over conventional inhaled dosage forms.

Thematic areas
Health & Biotech / Bio-medicals
Health & Biotech / New therapies
Health & Biotech / Nanomedicine
Health & Biotech / Development of new drugs
# Record card
20
Description

Therapeutic strategies targeting cell cycle in cancer have in general failed in the clinic since the drugs have lacked the therapeutic index required to achieve a robust response against cancer cells with little or no cytotoxic effect on normal cells. NEK6 kinase, which is implicated in cell cycle control, has recently emerged as an attractive target for the development of novel anticancer drugs with enhanced therapeutic index.

Thematic areas
Health & Biotech / Bio-medicals
Health & Biotech / New therapies
Health & Biotech / Development of new drugs
# Record card
35
Description

We have identified compounds that show a neuroprotective action in vivo, in models of neurodegenerative diseases (e.g. SMA, Parkinson, Alzheimer, Huntington) in the model organism C. elegans. These compounds consist of: mixtures of 22 natural extracts, 15 natural molecules and 11 synthetic molecules.

Thematic areas
Agrifood / Nutrition & health
Health & Biotech / Development of new drugs
Health & Biotech / Care, Hygiene, Cosmetics
# Record card
137
Description

With the advent of senolytic agents, capable of selectively removing senescent cells in “aged” tissues, the perception of age-associated diseases has changed from being an inevitable to a preventable phenomenon of human life. The present invention is part of this research topic with the identification of molecules with potential pro-apoptotic activity, specifically with senolytic activity. The computational approach adopted, is based on combining ligand-base and structure-based virtual screening.

Thematic areas
Health & Biotech
Health & Biotech / Micro and nanotechnology related to biological sciences
Health & Biotech / Bio-medicals
Health & Biotech / New therapies
Health & Biotech / Nanomedicine
Health & Biotech / Development of new drugs
# Record card
49
Description

Celiac disease and non-celiac gluten sensitivity affect a large portion of the world population. Furthermore, the percentage of people who adopt the gluten free diet is constantly increasing because it is perceived to be healthier. We have previously developed a food grade enzymatic procedure (transamidation) for wheat flour capable of making gluten unable to induce the inflammatory response in the intestine of celiac disease patients.

Thematic areas
Health & Biotech / New therapies
Agrifood / Nutrition & health
# Record card
157
Description

The technology concerns planar optical antennas composed of thin metal films and dielectric materials for the efficient direction of the light emitted by light sources, such as fluorescent molecules and bio-markers. They consist of a reflector layer, adjacent to the substrate, and a director, semi-reflective, between which the emitter is positioned, integrated into a homogeneous dielectric layer.

Thematic areas
ICT & Electronics
ICT & Electronics / Sensor/multi-sensor technology, instrumentation
Chemicals & Physics
Chemicals & Physics / Micro and nanotechnology related to physical, chemical and exact sciences
Chemicals & Physics / Quantum optics
Chemicals & Physics / Radiometry, photometry and vision
Chemicals & Physics / Atomic and molecular spectroscopy
Agrifood
Agrifood / Nutrition & health
Agrifood / Food quality & safety
Automotive transport and logistics
Health & Biotech
Health & Biotech / Biosensors
Health & Biotech / Diagnostic kits
Energy and environmental sustainability
Energy and environmental sustainability / Sensory
# Record card
140
Description

The technology refers to an innovative plasma (ionized gas) source operating at atmospheric pressure and low electric power levels. A cold plasma is produced, characterized by an ion temperature significantly lower than the electron temperature. Partial ionization of a Helium flux is induced by a time-varying electric field in between two parallel grids, both perpendicular to the flux itself.

Thematic areas
Health & Biotech
Health & Biotech / Bio-medicals
Health & Biotech / Care, Hygiene, Cosmetics
Health & Biotech / New therapies
Health & Biotech / Medical Device
Chemicals & Physics
Chemicals & Physics / Cold Plasmas
# Record card
50
Description

This technology describe the synthesis of cross-linked polymeric materials in the form of macroporous gels based on poly (2-hydroxyethyl methacrylate), capable of sequestering the anticoagulant heparin from aqueous solutions, physiological solutions and biological fluids. They are morphologically elastic and mechanically stable materials, and show high specificity and selectivity for heparin as demonstrated by the negligible adsorption of specific blood proteins such as antithrombin III, albumin and total proteins.

Thematic areas
Chemicals & Physics / Separation technologies
Health & Biotech / Medical Device
Materials / Plastics, polymers
# Record card
175
Description

The invention is a synthetic method to prepare colloidal nanomaterials of V-VI-VII semiconductors that do not contain toxic elements. This is the first method for the synthesis of mixed anion nanomaterials without toxic elements at large, which permitted to obtain, among others, bismuth chalcohalide nanocrystals that are arguably considered as one of main candidates to be the next big thing for light energy conversion.

Thematic areas
Materials
Materials / Processes of production & treatment of materials
Chemicals & Physics
Chemicals & Physics / Micro and nanotechnology related to physical, chemical and exact sciences
Materials / Semiconductors and Superconductors
Energy and environmental sustainability
Energy and environmental sustainability / Renewable sources
Energy and environmental sustainability / Energy production, transmission and conversion
ICT & Electronics
ICT & Electronics / Nanotechnologies related to electronics and microelectronics
Chemicals & Physics / Inorganic substances
Chemicals & Physics / Colours & dyes
Materials / Composite and hybrid materials
Materials / Optical materials
# Record card
32
Description

The full face mask adapts to the face of the user; it is used in the medical field where there may be close contact between a patient and a doctor and in all those areas of possible social overcrowding that, in case of a pandemic, may lead to the spread of a virus. To date, as the main means of containment and prevention of infection, are used masks made of fabric or equipped with filter that adhere to the face of the user in order to shield nose and mouth and / or filter the air inhaled and / or exhaled by the user.

Thematic areas
Health & Biotech / Medical Device
# Record card
40
Description

Recently, it has been demonstrated that Raman spectroscopy can play a fundamental role in assisting the work of the anatomopathologist by allowing classification of oncological samples with practically 100% accuracy in oncological diagnosis.

Thematic areas
Health & Biotech / Micro and nanotechnology related to biological sciences
Health & Biotech / Nanomedicine
Health & Biotech / Diagnostic, Medical imaging & advanced bioimaging
Chemicals & Physics / Micro and nanotechnology related to physical, chemical and exact sciences
ICT & Electronics / Artificial Intelligence
# Record card
67
Description

This is a high-throughput sequencing based method to map euchromatin and heterochromatin accessibility. The method is based on the sequential extraction of distinct nuclear fractions containing: soluble proteins (S1 fraction); the surnatant obtained after DNase treatment (S2 fraction); DNase-resistant chromatin extracted with high salt buffer (S3 fraction); and the most condensed and insoluble portion of chromatin, extracted with urea buffer that solubilizes the remaining proteins and membranes (S4 fraction).

Thematic areas
Health & Biotech / Bio-medicals
Health & Biotech / Diagnostic kits
# Record card
88
Description

TNBC affects around 170,000 patients worldwide each year and accounts for 15-20% of breast cancer; compared to other types of breast cancer, TNBC is more aggressive and precocious. Its diagnosis, made difficult by the existence of subtypes with different characteristics, is fundamental to establish prognosis and personalized therapy. Nucleic acid aptamers are highly selective low-molecular-weight molecules, synthesizable at low cost and easily modifiable, capable of binding and detecting tissue markers ("aptahistochemistry”). Our team has iden

Thematic areas
Health & Biotech / Diagnostic kits
# Record card
103
Description

The proposing team that works at CNR ISTEC has recently patented a technology for the production of the Smart Polycrystals (SP), i.e. transparent YAG-based ceramic polycrystals (Y3Al5O12) variably doped with rare earths ions and transition metals ions. The SPs solve the problem of the reduction of the efficiency in the solid state laser systems caused by the inhomogeneous heating of the single crystals during the emission process.

Thematic areas
Materials / Ceramic materials
Materials / Optical materials
Health & Biotech / Medical imaging & equipment
Additive and advanced industrial manufacturing
# Record card
139
Description

The study of proteins is typically limited to notions, sometimes with the aid of virtual 3D models, obtained from visualization programs. A knowledge of this type, although useful, limits the ability to acquire a more direct knowledge, almost never leads to awareness of dimensions, and is particularly difficult for those who do not have a strong capacity for three-dimensional imagination.

Thematic areas
Health & Biotech
Health & Biotech / Bio-informatics
Tourism, social sciences and cultural heritage / Technologies for preservation of cultural heritage
Tourism, social sciences and cultural heritage / Education & learning
Tourism, social sciences and cultural heritage / Entertainment
Tourism, social sciences and cultural heritage / Socio-economic models
Tourism, social sciences and cultural heritage / Multimedia technologies