Technologies | Promo-TT Instrument

Technologies

In this section it is possible to view, also through targeted research, the technologies inserted in the PROMO-TT Database. For further information on the technologies and to contact the CNR Research Teams who developed them, it is necessary to contact the Project Manager (see the references at the bottom of each record card).

Displaying results 1 - 2 of 2

Long noncoding RNAs containing ultraconserved genomic region 8 as putative urinary biomarker for bladder cancer detection

# Record card

Description

In our recent publication we identified a group of bladder cancer-specific ncRNA, called T-UCRs that are the most up-regulated in bladder cancer patient samples compared with normal bladder urothelium.

Thematic areas

Health & Biotech / Bio-medicals

Health & Biotech / Diagnostic kits

Mutated neurotrophic peptide for the treatment of neurodegenerative and neuro-traumatic diseases

# Record card

Description

We have identified the presence of the poorly characterized precursor proNGF-A in human tissues, deposited its coding nucleotide sequence (GenBank MH358394) and demonstrated its neuroprotective and neurotrophic activity in vitro and in vivo. We inserted mutations into the native molecule, identified through computational analysis, which allow proNGF-A production by eukaryotic expression systems, through a method currently validated on a laboratory scale.

Thematic areas

Health & Biotech / Development of new drugs