Technologies

NANOINCICLO is a technology based on the use of nanostructured cyclodextrins (CDs) for the targeted delivery of drugs such as anticancer drugs, photodynamic drugs, anti-inflammatories, antivirals, antibacterials, nutraceuticals and metals with therapeutic and diagnostic properties. Successful CDs for the proposed technology are FDA-approved or in advanced pre-clinical investigational stage and include natural and functionalized, polymeric, and amphiphilic monomeric CDs.

Solid State Nuclear Magnetic Resonance spectroscopy (SSNMR) is today one of the most powerful techniques for characterizing solid and soft materials and systems. This spectroscopy allows the detailed characterization of structural and dynamic properties over large spatial (0.1-100 nm) and time (10²-10^-11 s) scales. Accessing these properties allows a deep knowledge of a material to be obtained and  its design and optimization to be oriented.

Combinations of several enzymes in a production chain are preferred to “first generation” enzymatic processes (where the "single reaction - single enzyme" principle was followed), for the synthesis of compounds with high added value starting from simple and cheap substrates. An important requirement for obtaining control in "cascade enzymatic reactions" is the ability to deliver from one biocatalyst to the next one the various intermediates, limiting as much as possible the diffusion of the latter in the solvent.

The technology concerns planar optical antennas composed of thin metal films and dielectric materials for the efficient direction of the light emitted by light sources, such as fluorescent molecules and bio-markers. They consist of a reflector layer, adjacent to the substrate, and a director, semi-reflective, between which the emitter is positioned, integrated into a homogeneous dielectric layer.

Spark anemometry based on the analysis of an electrical discharge can be implemented in the automotive sector through measurements of the secondary circuit voltage. Actual applicability of this method is quite limited, given that it requires additional hardware that is not compatible with space requirements specific for production engines (e.g. fueled with gasoline, LPG or methane); furthermore, applying high voltage measurements is complex and entails increased cost.

The proposed technology is about the development of an innovative sunscreen obtained from cod fish bones, according to the principles of the circular economy. The sunscreen is a reddish powder, which is constituted of hydroxyapatite (a calcium phosphate main component of human bones) modified with iron. It is prepared with a simple and easily scalable process (treatment of the bones in Fe solution and successively at T = 700 oC) and could be adapted for bones of other fishes. 

Electrochromism is an optoelectronic characteristic of particular interest because it can be exploited in the creation of technologies such as smart windows (Smart Windows) to promote energy efficiency, automotive, sensor or visualization devices. Electrochromic materials change their optoelectronic characteristics, showing different colors depending on the applied electric field.

The technology refers to a system for the safety and control of the mobility of vehicles, pedestrians, and mass transport users, in conventional and advanced contexts and is suitable for use as an infrastructure for the production/sharing of information and data, aimed at monitoring and intervention in critical areas by offering specific functions concerning the detection of potentially dangerous situations or the optimization of resources.

The substitution of fossil derived monomers in thermosetting resins is a very important point to look at to face environmental impact issues related with the use of traditional resins. The research group set up a protocol for the preparation of thermosetting resins starting from vegetable oils with different composition to substitute the petroleum-based monomers. The materials obtained in this way have a bio-based carbon content higher than 80%.

IMM has developed tactile sensors for the detection of objects and surface and for the handling of objects with humanoid robots (e-skin). These devices can be integrated on ultra-flexible and high conformable substrates and they can be used for multiple applications: 1) for a correct interaction with objects distributed in complex environment; 2) for a safe short-range interaction between humanoid robot and humans; 3) for fabricating smart wearables for the detection of biometric parameters (e.g. heartbeat); 4) for remotely control rovers with wearable gadgets.

Geopolymers belong to the class of chemically bonded ceramics: they are synthesized at low temperatures and are eco-friendly, as besides the low consolidation temperature required by the process they can be produced from secondary raw materials and industrial waste of various kinds, thus reducing the energy demand and the environmental impact of the entire production cycle. Materials such as fly ash, steel mill slag, biomass ash, sludge and silt, extractive residues, mineral and ceramic powders, organic or inorganic waste fibers, plastics, etc.

Safe, efficient and specific nano-delivery systems are increasingly needed for precision and regenerative medicine and targeted therapies (e.g. anticancer and antimicrobial therapies), as well as for  the cosmetic and nutraceutical sectors’ applications. Despite the appreciable success of synthetic nanovectors, like for example liposomes, their clinical and market application is hampered by some limitations: • large scale production, • low cost production • intrinsic toxicity • limited cellular uptake • limited consumer acceptance.