Technologies

In this section it is possible to view, also through targeted research, the technologies inserted in the PROMO-TT Database. For further information on the technologies and to contact the CNR Research Teams who developed them, it is necessary to contact the Project Manager (see the references at the bottom of each record card).

Displaying results 1 - 10 of 10

# Record card
159
Description

The development of genome editing tools has revolutionized the way we think and deal with genetics. The use of Cas9 or its variants allows modifications of specific sites in the human genome by inducing deletions and insertions in a more or less controlled way. In recent years, a new class of tools for genome editing has emerged: the base editors (BE), which result from the fusion of a modified Cas9, which serves to direct the BE to the target, and an active deaminase acting on the DNA, which mediates the C> T or A> G editing.

Thematic areas
Health & Biotech
Health & Biotech / Bio-medicals
Health & Biotech / New therapies
Health & Biotech / Diagnostic kits
# Record card
80
Description

Time-correlated single photon counting (TCSPC) is regarded as the “gold-standard” method for fluorescence lifetime measurements. However, TCSPC requires using highly sensitive detectors, not suitable for measurements under bright light conditions, thereby making the use impractical in clinical settings. The invention described here solves this problem by synchronizing the fluorescence detection with an external light source.

Thematic areas
Health & Biotech / Smart Devices for Health and Wellness
Health & Biotech / Diagnostic, Medical imaging & advanced bioimaging
Health & Biotech / Medical Device
Health & Biotech / Biosensors
Health & Biotech / Bio-medicals
Health & Biotech / Medical imaging & equipment
Health & Biotech / Diagnostic kits
Health & Biotech / Bio-informatics
# Record card
61
Description

The compact-GC platform is a MEMS-based analytical module for the purge&trap pre-concentration and (gas)-chromatographic separation of a sample. The two analytical MEMS (pre-concentrator and GC column) are interconnected by means of a MEMS microfluidic manifold. The microfluidic manifold interconnects the analytical MEMS, but it also acts as injector through the integrated micro-valves.

Thematic areas
Tourism, social sciences and cultural heritage / Archeometry
Energy and environmental sustainability / Safety and security
ICT & Electronics / Sensor/multi-sensor technology, instrumentation
Materials / Processes of production & treatment of materials
Health & Biotech / Smart Devices for Health and Wellness
Agrifood / Food quality & safety
Energy and environmental sustainability / Energy production, transmission and conversion
Energy and environmental sustainability / Cleaner use of fossil fuels
Tourism, social sciences and cultural heritage / Safety and security
ICT & Electronics / Nanotechnologies related to electronics and microelectronics
Energy and environmental sustainability / Environmental engineering/technologies
Additive and advanced industrial manufacturing / Process control and logistic
Energy and environmental sustainability / Sensory
ICT & Electronics / Electronics and microelectronics
Chemicals & Physics / Separation technologies
# Record card
62
Description

We propose a portable chemical analysis system capable of identifying chemical substances at trace concentrations (sub-ppm), even in case of a complex matrix of interfering species.

Thematic areas
Tourism, social sciences and cultural heritage / Archeometry
Tourism, social sciences and cultural heritage / Safety and security
ICT & Electronics / Sensor/multi-sensor technology, instrumentation
ICT & Electronics / Optics & Acoustic
ICT & Electronics / Smart cities and Communities
ICT & Electronics / Robotics and control systems
ICT & Electronics / Optoacustic sensors, Optoelectronic devices
Additive and advanced industrial manufacturing / Process control and logistic
Chemicals & Physics / Separation technologies
Additive and advanced industrial manufacturing / Factory of the Future
Chemicals & Physics / Atomic and molecular spectroscopy
Health & Biotech / Smart Devices for Health and Wellness
Health & Biotech / Diagnostic, Medical imaging & advanced bioimaging
Energy and environmental sustainability / Safety and security
Health & Biotech / Medical Device
Energy and environmental sustainability / Natural disasters
Energy and environmental sustainability / Pollution treatment (air, soil, water)
Energy and environmental sustainability / Sensory
Measurement tools and Standards
ICT & Electronics / Electronics and microelectronics
# Record card
29
Description

The aim of the research group is the creation of 3D models (microorgan/ organoids) constructed using samples obtained from patients, both biopsy samples and samples collected with non-invasive techniques (exhaled breath condensate, induced sputum, blood samples).

Thematic areas
Health & Biotech / New therapies
Health & Biotech / Smart Devices for Health and Wellness
Health & Biotech / Medical Device
# Record card
262
Description

The proposal concerns the development of the G.A.T.CD4 (Gliadin-activated CD4+ T cells) method which allows, in peripheral blood, the identification of CD4+ T lymphocytes reactive to toxic peptides of gliadin, the main gluten protein of cereals.

Thematic areas
Health & Biotech
Health & Biotech / Bio-medicals
Health & Biotech / Diagnostic kits
Agrifood
Agrifood / Nutrition & health
# Record card
240
Description

"Transitional Wearable Companions'' (TWC) are interactive, multisensory, animal-shaped soft toys, developed as a support tool for early intervention in neurodevelopmental disorders (NDD), with particular reference to Autism Spectrum Disorders (ASD). Thanks to internal electronics, TWC can emit coloured lights, nice sounds and mild vibrations when touched on the paws. Such stimulations are usually very reinforcing to children and attract their attention.

Thematic areas
Health & Biotech
Health & Biotech / Smart Devices for Health and Wellness
ICT & Electronics
ICT & Electronics / Electronics and microelectronics
# Record card
157
Description

The technology concerns planar optical antennas composed of thin metal films and dielectric materials for the efficient direction of the light emitted by light sources, such as fluorescent molecules and bio-markers. They consist of a reflector layer, adjacent to the substrate, and a director, semi-reflective, between which the emitter is positioned, integrated into a homogeneous dielectric layer.

Thematic areas
ICT & Electronics
ICT & Electronics / Sensor/multi-sensor technology, instrumentation
Chemicals & Physics
Chemicals & Physics / Micro and nanotechnology related to physical, chemical and exact sciences
Chemicals & Physics / Quantum optics
Chemicals & Physics / Radiometry, photometry and vision
Chemicals & Physics / Atomic and molecular spectroscopy
Agrifood
Agrifood / Nutrition & health
Agrifood / Food quality & safety
Automotive transport and logistics
Health & Biotech
Health & Biotech / Biosensors
Health & Biotech / Diagnostic kits
Energy and environmental sustainability
Energy and environmental sustainability / Sensory
# Record card
67
Description

This is a high-throughput sequencing based method to map euchromatin and heterochromatin accessibility. The method is based on the sequential extraction of distinct nuclear fractions containing: soluble proteins (S1 fraction); the surnatant obtained after DNase treatment (S2 fraction); DNase-resistant chromatin extracted with high salt buffer (S3 fraction); and the most condensed and insoluble portion of chromatin, extracted with urea buffer that solubilizes the remaining proteins and membranes (S4 fraction).

Thematic areas
Health & Biotech / Bio-medicals
Health & Biotech / Diagnostic kits
# Record card
138
Description

We present a technology for the multiscale isolation (analytical-laboratory-production) of Extracellular Vesicles (VE), which overcomes the limitations of the currently available methods. As opposed to traditional "affinity-based" systems that exploit antibodies, our technology represents a radical paradigm shift in the development of affinity probes for vesicles, i.e.

Thematic areas
Health & Biotech
Health & Biotech / Smart Devices for Health and Wellness
Health & Biotech / Nanomedicine
Health & Biotech / Diagnostic, Medical imaging & advanced bioimaging
Health & Biotech / Regenerative Medicine
Health & Biotech / Care, Hygiene, Cosmetics
Health & Biotech / Biosensors
Health & Biotech / Micro and nanotechnology related to biological sciences
Health & Biotech / Bio-medicals
Health & Biotech / Diagnostic kits
Chemicals & Physics
Chemicals & Physics / Separation technologies