Technologies

In this section it is possible to view, also through targeted research, the technologies inserted in the PROMO-TT Database. For further information on the technologies and to contact the CNR Research Teams who developed them, it is necessary to contact the Project Manager (see the references at the bottom of each record card).

Displaying results 1 - 13 of 13

# Record card
89
Description

Nowadays, to properly design and develop advanced materials capable to preserve for long times their performance under aggressive environments such as power generation plants, renewables, nuclear reactors and electronics of new generation, transport on ground and on space, aeronautics, catalysis, biomedical implants, the optimization of metallurgical processes involved is crucial.

Thematic areas
Aerospace and Earth Science / Space sciences
Aerospace and Earth Science / Aeronautical technologies and avionics
Aerospace and Earth Science / Satellite technologies
Automotive transport and logistics / Vehicles
Automotive transport and logistics / Shipbuilding
Automotive transport and logistics / Propulsion
Automotive transport and logistics / Transport infrastructures
Additive and advanced industrial manufacturing / Additive manufacturing processes and materials
Additive and advanced industrial manufacturing / Vacuum/High vacuum technologies
Chemicals & Physics / Inorganic substances
Chemicals & Physics / Man made fibres
Chemicals & Physics / Special chemicals
Chemicals & Physics / Subtainable substances and green chemistry
Materials / Building materials
Materials / Ceramic materials
Materials / Composite and hybrid materials
Materials / Metals & alloys
Materials / Properties of materials, corrosion, degradation
Materials / Semiconductors and Superconductors
Energy and environmental sustainability / Renewable sources
Energy and environmental sustainability / Rational use of energy
Energy and environmental sustainability / Nuclear fission/nuclear fusion
Energy and environmental sustainability / Cleaner use of fossil fuels
Energy and environmental sustainability / Nuclear engineering
Energy and environmental sustainability / Safety and security
Energy and environmental sustainability / Environmental engineering/technologies
Energy and environmental sustainability / Building materials
Health & Biotech / Bio-medicals
# Record card
69
Description

The aim of the present invention is to develop a modular scintigraphic device, with high spatial resolution, capable of creating investigation areas of various shapes and sizes, of compact form and of being used in different types of applications.

Thematic areas
Health & Biotech / Bio-medicals
Health & Biotech / Medical imaging & equipment
Health & Biotech / Diagnostic, Medical imaging & advanced bioimaging
Health & Biotech / Medical Device
# Record card
42
Description

The present invention relates to a gamma camera for intracavitary use, which is widely used in the field of radio-guided surgery (intra-operative and laparoscopic and robotic-assisted) for the localisation of lymph nodes and tumours and/or other pathologies. The aim of the present invention is to make available an intraoperative tool able to overcome the drawbacks of the present known art.

Thematic areas
Health & Biotech / Bio-medicals
Health & Biotech / Medical imaging & equipment
Health & Biotech / Diagnostic, Medical imaging & advanced bioimaging
Health & Biotech / Medical Device
# Record card
52
Description

Silicon nanowires (SiNWs) are 1D structures with diameter ranging from few tens to hundreds of nanometers and length varying from few tens of nanometers to millimiters. SiNWs are fabricated in the labs of the IMM-CNR, Rome Unit,  by using bottom-up technologies such as plasma enhanced chemical vapor deposition (PECVD) at low growth temperature ((≤350°C), allowing the use of plastic and glassy substrates. Their electrical properties can be tuned by controlling the p/n doping during the growth.

Thematic areas
Health & Biotech / Nanomedicine
Health & Biotech / Diagnostic, Medical imaging & advanced bioimaging
Health & Biotech / Biosensors
Health & Biotech / Micro and nanotechnology related to biological sciences
Health & Biotech / Medical imaging & equipment
Health & Biotech / Smart Devices for Health and Wellness
Materials / Composite and hybrid materials
Materials / Metals & alloys
Materials / Optical materials
Materials / Processes of production & treatment of materials
Materials / Semiconductors and Superconductors
Chemicals & Physics / Micro and nanotechnology related to physical, chemical and exact sciences
ICT & Electronics / Optics & Acoustic
ICT & Electronics / Optoacustic sensors, Optoelectronic devices
ICT & Electronics / Nanotechnologies related to electronics and microelectronics
ICT & Electronics / Electronics and microelectronics
Energy and environmental sustainability / Sensory
# Record card
57
Description

Inert biomedical devices with modular load-bearing function designed with peculiar multi-domain composite microstructures. The reference compositional system is Zirconia-Alumina with a prevailing overall composition of customizable zirconia or alumina. Examples of devices are 3D structures consisting of parts with differentiated functional properties, due to different composition/microstructure/architecture, and further functionalizable ex-post to favor and improve the stabilization of the implantation by newly formed bone in superior quantity and quality.

Thematic areas
Health & Biotech / Bio-medicals
Materials / Ceramic materials
Materials / Composite and hybrid materials
# Record card
252
Description

Extracellular vesicles produced by teratocarcinoma cells were isolated and characterized. Functional assays on glioblastoma (GBM) cell cultures showed the inhibitory effect of these vesicles on tumor cell migration, without inducing undesirable effects such as increased cell proliferation or chemotherapy resistance.

Thematic areas
Health & Biotech
Health & Biotech / Micro and nanotechnology related to biological sciences
Health & Biotech / Bio-medicals
Health & Biotech / New therapies
Health & Biotech / Nanomedicine
Health & Biotech / Development of new drugs
# Record card
20
Description

Therapeutic strategies targeting cell cycle in cancer have in general failed in the clinic since the drugs have lacked the therapeutic index required to achieve a robust response against cancer cells with little or no cytotoxic effect on normal cells. NEK6 kinase, which is implicated in cell cycle control, has recently emerged as an attractive target for the development of novel anticancer drugs with enhanced therapeutic index.

Thematic areas
Health & Biotech / Bio-medicals
Health & Biotech / New therapies
Health & Biotech / Development of new drugs
# Record card
137
Description

With the advent of senolytic agents, capable of selectively removing senescent cells in “aged” tissues, the perception of age-associated diseases has changed from being an inevitable to a preventable phenomenon of human life. The present invention is part of this research topic with the identification of molecules with potential pro-apoptotic activity, specifically with senolytic activity. The computational approach adopted, is based on combining ligand-base and structure-based virtual screening.

Thematic areas
Health & Biotech
Health & Biotech / Micro and nanotechnology related to biological sciences
Health & Biotech / Bio-medicals
Health & Biotech / New therapies
Health & Biotech / Nanomedicine
Health & Biotech / Development of new drugs
# Record card
40
Description

Recently, it has been demonstrated that Raman spectroscopy can play a fundamental role in assisting the work of the anatomopathologist by allowing classification of oncological samples with practically 100% accuracy in oncological diagnosis.

Thematic areas
Health & Biotech / Micro and nanotechnology related to biological sciences
Health & Biotech / Nanomedicine
Health & Biotech / Diagnostic, Medical imaging & advanced bioimaging
Chemicals & Physics / Micro and nanotechnology related to physical, chemical and exact sciences
ICT & Electronics / Artificial Intelligence
# Record card
67
Description

This is a high-throughput sequencing based method to map euchromatin and heterochromatin accessibility. The method is based on the sequential extraction of distinct nuclear fractions containing: soluble proteins (S1 fraction); the surnatant obtained after DNase treatment (S2 fraction); DNase-resistant chromatin extracted with high salt buffer (S3 fraction); and the most condensed and insoluble portion of chromatin, extracted with urea buffer that solubilizes the remaining proteins and membranes (S4 fraction).

Thematic areas
Health & Biotech / Bio-medicals
Health & Biotech / Diagnostic kits
# Record card
41
Description

The technology is intended to face the main problems of transmucosal dental implants, such as peri-implant mucositis, peri-implantitis and epithelial downgrowth. The strategy foresees the development of a surface able to favor soft tissues growth (gum sealing), limit at the implant collar these tissues, reduce bacterial adhesion and eventually have an antibacterial action.

Thematic areas
Health & Biotech / Micro and nanotechnology related to biological sciences
Health & Biotech / Medical Device
Materials / Processes of production & treatment of materials
Chemicals & Physics / Micro and nanotechnology related to physical, chemical and exact sciences
# Record card
138
Description

We present a technology for the multiscale isolation (analytical-laboratory-production) of Extracellular Vesicles (VE), which overcomes the limitations of the currently available methods. As opposed to traditional "affinity-based" systems that exploit antibodies, our technology represents a radical paradigm shift in the development of affinity probes for vesicles, i.e.

Thematic areas
Health & Biotech
Health & Biotech / Smart Devices for Health and Wellness
Health & Biotech / Nanomedicine
Health & Biotech / Diagnostic, Medical imaging & advanced bioimaging
Health & Biotech / Regenerative Medicine
Health & Biotech / Care, Hygiene, Cosmetics
Health & Biotech / Biosensors
Health & Biotech / Micro and nanotechnology related to biological sciences
Health & Biotech / Bio-medicals
Health & Biotech / Diagnostic kits
Chemicals & Physics
Chemicals & Physics / Separation technologies
# Record card
93
Description

Safe, efficient and specific nano-delivery systems are increasingly needed for precision and regenerative medicine and targeted therapies (e.g. anticancer and antimicrobial therapies), as well as for  the cosmetic and nutraceutical sectors’ applications. Despite the appreciable success of synthetic nanovectors, like for example liposomes, their clinical and market application is hampered by some limitations: • large scale production, • low cost production • intrinsic toxicity • limited cellular uptake • limited consumer acceptance.

Thematic areas
Health & Biotech / Micro and nanotechnology related to biological sciences
Materials / Processes of production & treatment of materials
Chemicals & Physics / Micro and nanotechnology related to physical, chemical and exact sciences
Agrifood / Marine resources
Agrifood / Nutrition & health
Health & Biotech / Nanomedicine
Health & Biotech / Development of new drugs
Chemicals & Physics / Subtainable substances and green chemistry
Health & Biotech / Regenerative Medicine