Technologies

In this section it is possible to view, also through targeted research, the technologies inserted in the PROMO-TT Database. For further information on the technologies and to contact the CNR Research Teams who developed them, it is necessary to contact the Project Manager (see the references at the bottom of each record card).

Displaying results 1 - 12 of 12

# Record card
161
Description

AIDD is an integrated tool and a radically new way to discovery new drugs for neurodegenerative diseases (Alzheimer’s, Epilepsy, Ageing, etc.).

Thematic areas
Health & Biotech
Health & Biotech / Bio-informatics
Health & Biotech / Smart Devices for Health and Wellness
Health & Biotech / Development of new drugs
Energy and environmental sustainability
Energy and environmental sustainability / Simulation
# Record card
80
Description

Time-correlated single photon counting (TCSPC) is regarded as the “gold-standard” method for fluorescence lifetime measurements. However, TCSPC requires using highly sensitive detectors, not suitable for measurements under bright light conditions, thereby making the use impractical in clinical settings. The invention described here solves this problem by synchronizing the fluorescence detection with an external light source.

Thematic areas
Health & Biotech / Smart Devices for Health and Wellness
Health & Biotech / Diagnostic, Medical imaging & advanced bioimaging
Health & Biotech / Medical Device
Health & Biotech / Biosensors
Health & Biotech / Bio-medicals
Health & Biotech / Medical imaging & equipment
Health & Biotech / Diagnostic kits
Health & Biotech / Bio-informatics
# Record card
25
Description

The Biocrystal Facility, a large multidisciplinary laboratory established at the Institute of Molecular Biology and Pathology (IBPM) of CNR, in collaboration with the Biochemistry Department of Sapienza University aims at supporting the italian scientists and the pharmaceutical companies in the research to find new drug and vaccine against the endemic and epidemic diseases through structure-based drug design.

Thematic areas
Health & Biotech / Bio-informatics
Health & Biotech / Nanomedicine
Health & Biotech / Development of new drugs
# Record card
298
Description

C-ImmSim is one of the most advanced computational models of the immune system. The software resorts to (bit or amino acid) strings to represent the “binding site” of cells and molecules. C-ImmSim is an agent-based model that includes the major classes of immune cells of the lymphoid lineage and some of the myeloid lineage. Helper T cells are divided into five phenotypes. B cells and plasma B are also divided into two phenotypes.

Thematic areas
Health & Biotech / New therapies
Health & Biotech / Bio-informatics
Health & Biotech / Smart Devices for Health and Wellness
Health & Biotech / Development of new drugs
# Record card
89
Description

Nowadays, to properly design and develop advanced materials capable to preserve for long times their performance under aggressive environments such as power generation plants, renewables, nuclear reactors and electronics of new generation, transport on ground and on space, aeronautics, catalysis, biomedical implants, the optimization of metallurgical processes involved is crucial.

Thematic areas
Aerospace and Earth Science / Space sciences
Aerospace and Earth Science / Aeronautical technologies and avionics
Aerospace and Earth Science / Satellite technologies
Automotive transport and logistics / Vehicles
Automotive transport and logistics / Shipbuilding
Automotive transport and logistics / Propulsion
Automotive transport and logistics / Transport infrastructures
Additive and advanced industrial manufacturing / Additive manufacturing processes and materials
Additive and advanced industrial manufacturing / Vacuum/High vacuum technologies
Chemicals & Physics / Inorganic substances
Chemicals & Physics / Man made fibres
Chemicals & Physics / Special chemicals
Chemicals & Physics / Subtainable substances and green chemistry
Materials / Building materials
Materials / Ceramic materials
Materials / Composite and hybrid materials
Materials / Metals & alloys
Materials / Properties of materials, corrosion, degradation
Materials / Semiconductors and Superconductors
Energy and environmental sustainability / Renewable sources
Energy and environmental sustainability / Rational use of energy
Energy and environmental sustainability / Nuclear fission/nuclear fusion
Energy and environmental sustainability / Cleaner use of fossil fuels
Energy and environmental sustainability / Nuclear engineering
Energy and environmental sustainability / Safety and security
Energy and environmental sustainability / Environmental engineering/technologies
Energy and environmental sustainability / Building materials
Health & Biotech / Bio-medicals
# Record card
45
Description

CNR-ISTEC develops geopolymer composites for thermostructural applications, such as: self-supporting cavities; thermal and acoustic insulation; thermal and fire barriers; high temperature coatings and damping; molds and cores for foundry; foams and refractory linings. Geopolymers are chemically bonded materials at T <300 ° C. Being inorganic polymers without water in the structure, they tolerate high temperatures: they are incombustible, do not emit gas or fumes and do not explode.

Thematic areas
Materials / Building materials
Materials / Ceramic materials
Materials / Composite and hybrid materials
Automotive transport and logistics / Vehicles
Automotive transport and logistics / Shipbuilding
Automotive transport and logistics / Propulsion
Aerospace and Earth Science / Aeronautical technologies and avionics
# Record card
150
Description

The virtual dynamic docking, carried out in the MOLBD3 lab of the Institute of Biophysics, allows the identification of new drugs through the structural information deriving from the study of target proteins, responsible for some human pathologies. In particular, we screen drugs or small molecules (commercial/own libraries) against known protein sites, surface cavities, surfaces of protein-protein interactions (fixed/rigid hotspots) or structural transition states (dynamic hotspots).

Thematic areas
Health & Biotech
Health & Biotech / Development of new drugs
Health & Biotech / Bio-medicals
Health & Biotech / Bio-informatics
# Record card
285
Description

Health360 is a software framework for building cloud platforms to monitor the health of subjects recruited in clinical trials, residents of social housing or athletes in sports teams. The framework is based on interconnected and configurable modules to implement platforms that meet specific needs while maintaining a high level of usability.

Thematic areas
ICT & Electronics / Sensor/multi-sensor technology, instrumentation
Health & Biotech / Medical imaging & equipment
Health & Biotech / Bio-informatics
ICT & Electronics / Information processing, information system, workflow management
Health & Biotech / Diagnostic, Medical imaging & advanced bioimaging
# Record card
68
Description

In the last years, genetics played a strategic role in the identification of therapeutic targets for complex diseases. Genetic studies identified thousands of variants contributing to disease onset and/or to the influence of measurable features (phenotypes) impacting health. The mechanism of action by which they modulate diseases and phenotypes is still unknown for the vast majority.

Thematic areas
Health & Biotech / Bio-informatics
ICT & Electronics / Big Data
# Record card
13
Description

The invention consists in a special regulation method of the horizontal axes of operating and rubbing wheels of a centerless grinding machine coupled with an opportune blade profile, allowing a continuous regulation of blade rest angle (angle between tangent to blade profile at the contact point with the work piece and the horizon, denoted by γ) and workpiece height (denoted by hw), without requiring blade substitution and/or manual regulations.

Thematic areas
Additive and advanced industrial manufacturing / Machine tools
Materials / Metals & alloys
# Record card
139
Description

The study of proteins is typically limited to notions, sometimes with the aid of virtual 3D models, obtained from visualization programs. A knowledge of this type, although useful, limits the ability to acquire a more direct knowledge, almost never leads to awareness of dimensions, and is particularly difficult for those who do not have a strong capacity for three-dimensional imagination.

Thematic areas
Health & Biotech
Health & Biotech / Bio-informatics
Tourism, social sciences and cultural heritage / Technologies for preservation of cultural heritage
Tourism, social sciences and cultural heritage / Education & learning
Tourism, social sciences and cultural heritage / Entertainment
Tourism, social sciences and cultural heritage / Socio-economic models
Tourism, social sciences and cultural heritage / Multimedia technologies
# Record card
46
Description

Geopolymers belong to the class of chemically bonded ceramics: they are synthesized at low temperatures and are eco-friendly, as besides the low consolidation temperature required by the process they can be produced from secondary raw materials and industrial waste of various kinds, thus reducing the energy demand and the environmental impact of the entire production cycle. Materials such as fly ash, steel mill slag, biomass ash, sludge and silt, extractive residues, mineral and ceramic powders, organic or inorganic waste fibers, plastics, etc.

Thematic areas
Materials / Processes of production & treatment of materials
Materials / Building materials
Chemicals & Physics / Inorganic substances
Energy and environmental sustainability / Building materials
Materials / Ceramic materials
Automotive transport and logistics / Vehicles
Automotive transport and logistics / Shipbuilding
Chemicals & Physics / Subtainable substances and green chemistry
Aerospace and Earth Science / Aeronautical technologies and avionics
Energy and environmental sustainability / Waste management