Technologies

In this section it is possible to view, also through targeted research, the technologies inserted in the PROMO-TT Database. For further information on the technologies and to contact the CNR Research Teams who developed them, it is necessary to contact the Project Manager (see the references at the bottom of each record card).

Displaying results 1 - 4 of 4

# Record card
42
Description

The present invention relates to a gamma camera for intracavitary use, which is widely used in the field of radio-guided surgery (intra-operative and laparoscopic and robotic-assisted) for the localisation of lymph nodes and tumours and/or other pathologies. The aim of the present invention is to make available an intraoperative tool able to overcome the drawbacks of the present known art.

Thematic areas
Health & Biotech / Bio-medicals
Health & Biotech / Medical imaging & equipment
Health & Biotech / Diagnostic, Medical imaging & advanced bioimaging
Health & Biotech / Medical Device
# Record card
150
Description

The virtual dynamic docking, carried out in the MOLBD3 lab of the Institute of Biophysics, allows the identification of new drugs through the structural information deriving from the study of target proteins, responsible for some human pathologies. In particular, we screen drugs or small molecules (commercial/own libraries) against known protein sites, surface cavities, surfaces of protein-protein interactions (fixed/rigid hotspots) or structural transition states (dynamic hotspots).

Thematic areas
Health & Biotech
Health & Biotech / Development of new drugs
Health & Biotech / Bio-medicals
Health & Biotech / Bio-informatics
# Record card
68
Description

In the last years, genetics played a strategic role in the identification of therapeutic targets for complex diseases. Genetic studies identified thousands of variants contributing to disease onset and/or to the influence of measurable features (phenotypes) impacting health. The mechanism of action by which they modulate diseases and phenotypes is still unknown for the vast majority.

Thematic areas
Health & Biotech / Bio-informatics
ICT & Electronics / Big Data
# Record card
35
Description

We have identified compounds that show a neuroprotective action in vivo, in models of neurodegenerative diseases (e.g. SMA, Parkinson, Alzheimer, Huntington) in the model organism C. elegans. These compounds consist of: mixtures of 22 natural extracts, 15 natural molecules and 11 synthetic molecules.

Thematic areas
Agrifood / Nutrition & health
Health & Biotech / Development of new drugs
Health & Biotech / Care, Hygiene, Cosmetics