Diagnostics

This technology enables the development of “on-demand” genomic biomarkers, designed according to the target organism and the purpose (genetic diagnosis or wellness evaluation). These markers leverage DNA plasticity and rely on advanced 2nd and 3rd generation PCR techniques, allowing for a fast, flexible, and multispecies approach. Compared to traditional methods, they provide quicker, reliable, and cost-effective results.

The technology is an ultra-sensitive optical biosensor based on the FRET principle, designed for identifying the initial, pre-aggregated pathological form of the Tau protein (CST). The innovation lies in the ability to detect specific conformational changes (CST), providing a molecular advantage over concentration-only tests.

In vitro validation (TRL 3) has been successfully completed, demonstrating the sensor's effectiveness on:

VisLab laboratory of IMM possesses a latest generation Raman micro-spectroscope equipped for vibrational measurements with high spatial and spectral resolution, at controlled temperature and in fast-imaging. The apparatus can be used to collect information and chemico-physical maps without the need for sample preparation and alteration, therefore for non-destructive studies and in operating conditions.