Technologies

In this section it is possible to view, also through targeted research, the technologies inserted in the PROMO-TT Database. For further information on the technologies and to contact the CNR Research Teams who developed them, it is necessary to contact the Project Manager (see the references at the bottom of each record card).

Displaying results 1 - 14 of 14

# Record card
239
Description

Bivalve mollusc shells are made mainly of CaCO3 (ca 95%), with a small fraction of organic material. If from these shells this mineral is retrieved, they could become a renewable and sustainable “mine” of a “blue” CaCO3. Bivalve mollusc shells, also after the removal of the animal flesh, maintain a certain quantity of organic substances, part in the muscle and part in the shell.

Thematic areas
Bioeconomy
Energy and environmental sustainability
Energy and environmental sustainability / Renewable sources
Health & Biotech
Health & Biotech / Care, Hygiene, Cosmetics
Energy and environmental sustainability / Waste management
Additive and advanced industrial manufacturing
Energy and environmental sustainability / Pollution treatment (air, soil, water)
Chemicals & Physics
Chemicals & Physics / Inorganic substances
Additive and advanced industrial manufacturing / Additive manufacturing processes and materials
Materials
Materials / Ceramic materials
Chemicals & Physics / Subtainable substances and green chemistry
Materials / Paper technology
Materials / Plastics, polymers
# Record card
159
Description

The development of genome editing tools has revolutionized the way we think and deal with genetics. The use of Cas9 or its variants allows modifications of specific sites in the human genome by inducing deletions and insertions in a more or less controlled way. In recent years, a new class of tools for genome editing has emerged: the base editors (BE), which result from the fusion of a modified Cas9, which serves to direct the BE to the target, and an active deaminase acting on the DNA, which mediates the C> T or A> G editing.

Thematic areas
Health & Biotech
Health & Biotech / Bio-medicals
Health & Biotech / New therapies
Health & Biotech / Diagnostic kits
# Record card
247
Description

The present invention relates to the biomedical sector of the treatment of lung diseases and related symptoms. In particular, the present invention provides compositions and methods based on the use of selected polymeric biomaterials, in combination with stem cells and/or their secretome, capable of synergistically improving the development, regeneration and repair of chronic lung injuries and related symptoms.

Thematic areas
Health & Biotech
Health & Biotech / New therapies
Materials
Materials / Composite and hybrid materials
Health & Biotech / Medical Device
Health & Biotech / Regenerative Medicine
# Record card
129
Description

Lifeshell is an anti-seismic furniture construction concept, which can be used for making wardrobes, tables, desktops, beds. It’s made by timber based panels: highly resistant and flexible, relatively lightweight and inexpensive. Lifeshell benefits from the natural wood elasticity and from smart connections for dissipating the great impact energies occurring during an earthquake. Lifeshell has been designed for resisting partial building collapses, and to provide a safe shell where inhabitants can find refuge.

Thematic areas
Aerospace and Earth Science
Aerospace and Earth Science / Seismology
Materials
Materials / Wood products
Energy and environmental sustainability / Building materials
Agrifood
Agrifood / Forestry
Health & Biotech
Health & Biotech / Smart Devices for Health and Wellness
Energy and environmental sustainability
Tourism, social sciences and cultural heritage / Safety and security
Energy and environmental sustainability / Natural disasters
Energy and environmental sustainability / Simulation
Tourism, social sciences and cultural heritage
Tourism, social sciences and cultural heritage / Technologies for preservation of cultural heritage
Bioeconomy
# Record card
252
Description

Extracellular vesicles produced by teratocarcinoma cells were isolated and characterized. Functional assays on glioblastoma (GBM) cell cultures showed the inhibitory effect of these vesicles on tumor cell migration, without inducing undesirable effects such as increased cell proliferation or chemotherapy resistance.

Thematic areas
Health & Biotech
Health & Biotech / Micro and nanotechnology related to biological sciences
Health & Biotech / Bio-medicals
Health & Biotech / New therapies
Health & Biotech / Nanomedicine
Health & Biotech / Development of new drugs
# Record card
63
Description

Integrative omics has posed new challenges in modern precision medicine, particularly in oncology, including i) the identification of new tumor markers for early, precise, and non-invasive diagnostics, and ii) the discovery of innovative molecular targets for therapeutic applications. Our studies on medulloblastoma, a highly malignant childhood tumor, have contributed to identifying RNA molecules that meet these criteria.

Thematic areas
Health & Biotech / New therapies
# Record card
29
Description

The aim of the research group is the creation of 3D models (microorgan/ organoids) constructed using samples obtained from patients, both biopsy samples and samples collected with non-invasive techniques (exhaled breath condensate, induced sputum, blood samples).

Thematic areas
Health & Biotech / New therapies
Health & Biotech / Smart Devices for Health and Wellness
Health & Biotech / Medical Device
# Record card
74
Description

The object of the technology is the development of a transferable methodology from the laboratory scale to the pilot scale to be validated in the industrial setting for the treatment of basic waste of natural polymers of agro-food or manufacturing industry.

Thematic areas
Materials / Properties of materials, corrosion, degradation
Additive and advanced industrial manufacturing / Packaging
Energy and environmental sustainability / Renewable sources
Chemicals & Physics / Plastics & rubber
Chemicals & Physics / Subtainable substances and green chemistry
Energy and environmental sustainability / Waste management
Bioeconomy
# Record card
71
Description

Recently, nanoparticles and nanovesicles have been investigated as potential approaches for the treatment of neurodegenerative diseases. In particular, in the Biotech sector an increasingly deeper penetration of new treatment models and biological drugs based on cellular, subcellular and vesicle therapies is expected. The patent is based on the production of Myelin-based nanoVesicles (MyVes) produced by microfluidics, starting from myelin extracted from brain tissue. These vesicles find two major fields of applications as potential drugs or as supplements/nutraceuticals.

Thematic areas
Health & Biotech / Micro and nanotechnology related to biological sciences
Health & Biotech / Bio-medicals
Health & Biotech / New therapies
Health & Biotech / Nanomedicine
Health & Biotech / Development of new drugs
Agrifood / Nutrition & health
# Record card
33
Description

Severe asthma or chronic obstructive pulmonary disease (COPD) are nowadays associated with a poor response to corticosteroids which led to the use of high-dose with consequent improved onset of side effects. The use of nanotechnologies can represent an innovative approach for the effective treatment of both asthma and COPD. The development of new nano-formulations involving the use of nanomaterials and specifically tailored to be inhaled offers numerous advantages over conventional inhaled dosage forms.

Thematic areas
Health & Biotech / Bio-medicals
Health & Biotech / New therapies
Health & Biotech / Nanomedicine
Health & Biotech / Development of new drugs
# Record card
153
Description

To the enterprises working in the field of nutrition/nutraceutics and drug development/repositioning, we offer the know-how and state-of-the-art instrumentation of our labs to monitor multiple relevant biological parameters at the cellular level: metabolic activity, vitality, health, but also stress and toxicity. The use of advanced imaging techniques based on fluorescent/bioluminescent probes together with the availability of time-lapse acquisitions, guarantee the cutting-edge analysis of different biological parameters over time.

Thematic areas
Health & Biotech
Health & Biotech / Micro and nanotechnology related to biological sciences
Health & Biotech / Bio-medicals
Health & Biotech / New therapies
Health & Biotech / Diagnostic, Medical imaging & advanced bioimaging
Health & Biotech / Development of new drugs
Health & Biotech / Biosensors
Agrifood
Agrifood / Nutrition & health
Agrifood / Food quality & safety
# Record card
8
Description

Polymer development is approaching to a new stage of advancement in which new functionalities especially in combination with conductive polymers and nanomaterials are more effective. In this context the study of new composites is the key to enable the development of disruptive technologies as additive manufacturing. Increasing electrical conductivity open the way to a new class of objects to be prototyped rapidly at low cost with a high level of customization.

Thematic areas
ICT & Electronics / Laser technologies
Bioeconomy
Materials / Photo-active & graphene-based materials
Additive and advanced industrial manufacturing / Additive manufacturing processes and materials
Additive and advanced industrial manufacturing / Factory of the Future
Health & Biotech / Biosensors
# Record card
162
Description

Grape pomace, a by-product of wine-making, is rich in polyphenols, metals, organic acids and can become a functional ingredient in food and beverage. The stabilisation of the pomace has been optimised to preserve the anti-inflammatory and antioxidant properties of the molecules present. Isolated grape skins have been reused in purity or in blends with other plant components as a base for: 1) herbal teas, 2) ready-to-drink functional beverages, 3) freeze-dried products.

Thematic areas
Agrifood
Agrifood / Nutrition & health
Bioeconomy
Energy and environmental sustainability
Energy and environmental sustainability / Renewable sources
# Record card
21
Description

Our treatment demonstrated the ability to kill metastatic human melanoma cells, for which there are very few effective therapeutic approaches. Use of a specific Essential Oil (EO) to inhibit the replication of human metastatic melanoma cells. This EO can be used both for direct application to the skin, and administered by mouth to reach both primary and metastatic melanomas.

Thematic areas
Agrifood / Nutrition & health
Health & Biotech / Regenerative Medicine
Health & Biotech / New therapies