Technologies

In this section it is possible to view, also through targeted research, the technologies inserted in the PROMO-TT Database. For further information on the technologies and to contact the CNR Research Teams who developed them, it is necessary to contact the Project Manager (see the references at the bottom of each record card).

Displaying results 1 - 15 of 21

# Record card
12
Description

Current standard SPECTs, in order to achieve high resolutions, use a multi-pinholes technology that requires numerous data processing to limit the effects of image distortion. The proposed SSR-SPECT scanner, uses a parallel-hole collimator and therefore does not require numerical reprocessing of the data to obtain correct information on the images, while assuring spatial resolutions close to those of the pinholes through the acquisition of sequences of images shifted from one to another.

Thematic areas
Health & Biotech / Bio-medicals
Health & Biotech / Medical imaging & equipment
Health & Biotech / Diagnostic, Medical imaging & advanced bioimaging
# Record card
159
Description

The development of genome editing tools has revolutionized the way we think and deal with genetics. The use of Cas9 or its variants allows modifications of specific sites in the human genome by inducing deletions and insertions in a more or less controlled way. In recent years, a new class of tools for genome editing has emerged: the base editors (BE), which result from the fusion of a modified Cas9, which serves to direct the BE to the target, and an active deaminase acting on the DNA, which mediates the C> T or A> G editing.

Thematic areas
Health & Biotech
Health & Biotech / Bio-medicals
Health & Biotech / New therapies
Health & Biotech / Diagnostic kits
# Record card
70
Description

The technology we participate to develop, called "Zinc-Finger Artificial Transcription Factors (ZF-ATFs)", allows to design, realize and select artificial genes coding for proteins capable of recognizing and binding "potentially" any DNA sequence. We used ZF-ATF technology to reprogram the expression of "beneficial" genes capable of efficiently counteracting the negative effect of mutated genes related to rare diseases.

Thematic areas
Health & Biotech / Bio-medicals
Health & Biotech / New therapies
# Record card
80
Description

Time-correlated single photon counting (TCSPC) is regarded as the “gold-standard” method for fluorescence lifetime measurements. However, TCSPC requires using highly sensitive detectors, not suitable for measurements under bright light conditions, thereby making the use impractical in clinical settings. The invention described here solves this problem by synchronizing the fluorescence detection with an external light source.

Thematic areas
Health & Biotech / Smart Devices for Health and Wellness
Health & Biotech / Diagnostic, Medical imaging & advanced bioimaging
Health & Biotech / Medical Device
Health & Biotech / Biosensors
Health & Biotech / Bio-medicals
Health & Biotech / Medical imaging & equipment
Health & Biotech / Diagnostic kits
Health & Biotech / Bio-informatics
# Record card
69
Description

The aim of the present invention is to develop a modular scintigraphic device, with high spatial resolution, capable of creating investigation areas of various shapes and sizes, of compact form and of being used in different types of applications.

Thematic areas
Health & Biotech / Bio-medicals
Health & Biotech / Medical imaging & equipment
Health & Biotech / Diagnostic, Medical imaging & advanced bioimaging
Health & Biotech / Medical Device
# Record card
61
Description

The compact-GC platform is a MEMS-based analytical module for the purge&trap pre-concentration and (gas)-chromatographic separation of a sample. The two analytical MEMS (pre-concentrator and GC column) are interconnected by means of a MEMS microfluidic manifold. The microfluidic manifold interconnects the analytical MEMS, but it also acts as injector through the integrated micro-valves.

Thematic areas
Tourism, social sciences and cultural heritage / Archeometry
Energy and environmental sustainability / Safety and security
ICT & Electronics / Sensor/multi-sensor technology, instrumentation
Materials / Processes of production & treatment of materials
Health & Biotech / Smart Devices for Health and Wellness
Agrifood / Food quality & safety
Energy and environmental sustainability / Energy production, transmission and conversion
Energy and environmental sustainability / Cleaner use of fossil fuels
Tourism, social sciences and cultural heritage / Safety and security
ICT & Electronics / Nanotechnologies related to electronics and microelectronics
Energy and environmental sustainability / Environmental engineering/technologies
Additive and advanced industrial manufacturing / Process control and logistic
Energy and environmental sustainability / Sensory
ICT & Electronics / Electronics and microelectronics
Chemicals & Physics / Separation technologies
# Record card
42
Description

The present invention relates to a gamma camera for intracavitary use, which is widely used in the field of radio-guided surgery (intra-operative and laparoscopic and robotic-assisted) for the localisation of lymph nodes and tumours and/or other pathologies. The aim of the present invention is to make available an intraoperative tool able to overcome the drawbacks of the present known art.

Thematic areas
Health & Biotech / Bio-medicals
Health & Biotech / Medical imaging & equipment
Health & Biotech / Diagnostic, Medical imaging & advanced bioimaging
Health & Biotech / Medical Device
# Record card
28
Description

The portable device is intended to assess exposure to electromagnetic fields produced by an MRI equipment. The device (dosimeter) allows to improve the analysis and study of the problems related to the exposure of the operators, starting from the technical-scientific aspects related to the exposure, also allowing to create a manual of best practices as well as to improve the professional training of operators.

Thematic areas
Health & Biotech / Bio-medicals
ICT & Electronics / Electronics and microelectronics
# Record card
62
Description

We propose a portable chemical analysis system capable of identifying chemical substances at trace concentrations (sub-ppm), even in case of a complex matrix of interfering species.

Thematic areas
Tourism, social sciences and cultural heritage / Archeometry
Tourism, social sciences and cultural heritage / Safety and security
ICT & Electronics / Sensor/multi-sensor technology, instrumentation
ICT & Electronics / Optics & Acoustic
ICT & Electronics / Smart cities and Communities
ICT & Electronics / Robotics and control systems
ICT & Electronics / Optoacustic sensors, Optoelectronic devices
Additive and advanced industrial manufacturing / Process control and logistic
Chemicals & Physics / Separation technologies
Additive and advanced industrial manufacturing / Factory of the Future
Chemicals & Physics / Atomic and molecular spectroscopy
Health & Biotech / Smart Devices for Health and Wellness
Health & Biotech / Diagnostic, Medical imaging & advanced bioimaging
Energy and environmental sustainability / Safety and security
Health & Biotech / Medical Device
Energy and environmental sustainability / Natural disasters
Energy and environmental sustainability / Pollution treatment (air, soil, water)
Energy and environmental sustainability / Sensory
Measurement tools and Standards
ICT & Electronics / Electronics and microelectronics
# Record card
252
Description

Extracellular vesicles produced by teratocarcinoma cells were isolated and characterized. Functional assays on glioblastoma (GBM) cell cultures showed the inhibitory effect of these vesicles on tumor cell migration, without inducing undesirable effects such as increased cell proliferation or chemotherapy resistance.

Thematic areas
Health & Biotech
Health & Biotech / Micro and nanotechnology related to biological sciences
Health & Biotech / Bio-medicals
Health & Biotech / New therapies
Health & Biotech / Nanomedicine
Health & Biotech / Development of new drugs
# Record card
29
Description

The aim of the research group is the creation of 3D models (microorgan/ organoids) constructed using samples obtained from patients, both biopsy samples and samples collected with non-invasive techniques (exhaled breath condensate, induced sputum, blood samples).

Thematic areas
Health & Biotech / New therapies
Health & Biotech / Smart Devices for Health and Wellness
Health & Biotech / Medical Device
# Record card
262
Description

The proposal concerns the development of the G.A.T.CD4 (Gliadin-activated CD4+ T cells) method which allows, in peripheral blood, the identification of CD4+ T lymphocytes reactive to toxic peptides of gliadin, the main gluten protein of cereals.

Thematic areas
Health & Biotech
Health & Biotech / Bio-medicals
Health & Biotech / Diagnostic kits
Agrifood
Agrifood / Nutrition & health
# Record card
182
Description

An innovative approach for the treatment of diabetic and venous ulcers, characterized by a difficult healing process and therefore at potential risk of infection and therefore of hospitalization and amputation of the limb, is represented by the local administration of "bioactive" factors through the use of synthetic and/or biological matrices that allow a gradual and controlled release in order to obtain a better and faster healing.

Thematic areas
Health & Biotech
Health & Biotech / Bio-medicals
Health & Biotech / New therapies
Health & Biotech / Medical Device
Health & Biotech / Regenerative Medicine
# Record card
240
Description

"Transitional Wearable Companions'' (TWC) are interactive, multisensory, animal-shaped soft toys, developed as a support tool for early intervention in neurodevelopmental disorders (NDD), with particular reference to Autism Spectrum Disorders (ASD). Thanks to internal electronics, TWC can emit coloured lights, nice sounds and mild vibrations when touched on the paws. Such stimulations are usually very reinforcing to children and attract their attention.

Thematic areas
Health & Biotech
Health & Biotech / Smart Devices for Health and Wellness
ICT & Electronics
ICT & Electronics / Electronics and microelectronics
# Record card
71
Description

Recently, nanoparticles and nanovesicles have been investigated as potential approaches for the treatment of neurodegenerative diseases. In particular, in the Biotech sector an increasingly deeper penetration of new treatment models and biological drugs based on cellular, subcellular and vesicle therapies is expected. The patent is based on the production of Myelin-based nanoVesicles (MyVes) produced by microfluidics, starting from myelin extracted from brain tissue. These vesicles find two major fields of applications as potential drugs or as supplements/nutraceuticals.

Thematic areas
Health & Biotech / Micro and nanotechnology related to biological sciences
Health & Biotech / Bio-medicals
Health & Biotech / New therapies
Health & Biotech / Nanomedicine
Health & Biotech / Development of new drugs
Agrifood / Nutrition & health