Current standard SPECTs, in order to achieve high resolutions, use a multi-pinholes technology that requires numerous data processing to limit the effects of image distortion. The proposed SSR-SPECT scanner, uses a parallel-hole collimator and therefore does not require numerical reprocessing of the data to obtain correct information on the images, while assuring spatial resolutions close to those of the pinholes through the acquisition of sequences of images shifted from one to another. The technique is adaptable to experimental needs, allowing the quality of the images to be optimised according to the specifications of the examination required (by varying the number of images acquired). In addition, the introduction of CT phase contrast improves the morphological details that can be obtained. Thanks to the implementation of phase contrast, it will be possible to obtain a detailed description of biological tissues and the vascular system to be obtained without using external contrast agents.
Using patented technology (SSR - Super Spatial Resolution), it is possible to estimate an improvement of between 35-70% in nominal spatial resolution, compared to standard SPECT technology. The introduction of CT phase contrast improves the morphological details that can be obtained. With the implementation of phase contrast, it will be possible to achieve a contrast resolution up to 1000 times higher than that achievable with standard CT equipment. The technology is potentially applicable to theragnostic applications, e.g. integrating systems for controlled drug delivery using magnetic fields.
Italy, USA, PCT