Technologies

In this section it is possible to view, also through targeted research, the technologies inserted in the PROMO-TT Database. For further information on the technologies and to contact the CNR Research Teams who developed them, it is necessary to contact the Project Manager (see the references at the bottom of each record card).

Displaying results 1 - 7 of 7

# Record card
25
Description

The Biocrystal Facility, a large multidisciplinary laboratory established at the Institute of Molecular Biology and Pathology (IBPM) of CNR, in collaboration with the Biochemistry Department of Sapienza University aims at supporting the italian scientists and the pharmaceutical companies in the research to find new drug and vaccine against the endemic and epidemic diseases through structure-based drug design.

Thematic areas
Health & Biotech / Bio-informatics
Health & Biotech / Nanomedicine
Health & Biotech / Development of new drugs
# Record card
150
Description

The virtual dynamic docking, carried out in the MOLBD3 lab of the Institute of Biophysics, allows the identification of new drugs through the structural information deriving from the study of target proteins, responsible for some human pathologies. In particular, we screen drugs or small molecules (commercial/own libraries) against known protein sites, surface cavities, surfaces of protein-protein interactions (fixed/rigid hotspots) or structural transition states (dynamic hotspots).

Thematic areas
Health & Biotech
Health & Biotech / Development of new drugs
Health & Biotech / Bio-medicals
Health & Biotech / Bio-informatics
# Record card
71
Description

Recently, nanoparticles and nanovesicles have been investigated as potential approaches for the treatment of neurodegenerative diseases. In particular, in the Biotech sector an increasingly deeper penetration of new treatment models and biological drugs based on cellular, subcellular and vesicle therapies is expected. The patent is based on the production of Myelin-based nanoVesicles (MyVes) produced by microfluidics, starting from myelin extracted from brain tissue. These vesicles find two major fields of applications as potential drugs or as supplements/nutraceuticals.

Thematic areas
Health & Biotech / Micro and nanotechnology related to biological sciences
Health & Biotech / Bio-medicals
Health & Biotech / New therapies
Health & Biotech / Nanomedicine
Health & Biotech / Development of new drugs
Agrifood / Nutrition & health
# Record card
158
Description

Solid State Nuclear Magnetic Resonance spectroscopy (SSNMR) is today one of the most powerful techniques for characterizing solid and soft materials and systems. This spectroscopy allows the detailed characterization of structural and dynamic properties over large spatial (0.1-100 nm) and time (102-10-11 s) scales. Accessing these properties allows a deep knowledge of a material to be obtained and  its design and optimization to be oriented.

Thematic areas
ICT & Electronics
ICT & Electronics / Optoacustic sensors, Optoelectronic devices
ICT & Electronics / Nanotechnologies related to electronics and microelectronics
Additive and advanced industrial manufacturing
Additive and advanced industrial manufacturing / Packaging
Additive and advanced industrial manufacturing / Additive manufacturing processes and materials
Additive and advanced industrial manufacturing / Factory of the Future
Materials
Materials / Wood products
Health & Biotech
Health & Biotech / Nanomedicine
Health & Biotech / Diagnostic, Medical imaging & advanced bioimaging
Health & Biotech / Development of new drugs
Health & Biotech / Regenerative Medicine
Health & Biotech / Care, Hygiene, Cosmetics
Tourism, social sciences and cultural heritage
Tourism, social sciences and cultural heritage / Technologies for preservation of cultural heritage
Aerospace and Earth Science
Aerospace and Earth Science / Aeronautical technologies and avionics
Tourism, social sciences and cultural heritage / Multimedia technologies
Tourism, social sciences and cultural heritage / Archaeology
Agrifood
Agrifood / Agriculture
Agrifood / Food quality & safety
Automotive transport and logistics
Automotive transport and logistics / Vehicles
Automotive transport and logistics / Shipbuilding
Automotive transport and logistics / Innovative fuels
Chemicals & Physics
Energy and environmental sustainability
# Record card
177
Description

Filamentous bacteriophages for size, in vivo biodistribution and easiness of engineering, are considered as natural nanoparticles. The developed technology allows the construction of bio-nanoparticles based on filamentous bacteriophages delivering proteic antigens and immunomodulating lipids. Thanks to the high content of hydrophobic residues, phage capsid proteins have high binding affinity to lipids, allowing the conjugation of immunostimulating lipids.

Thematic areas
Health & Biotech
Health & Biotech / Nanomedicine
Health & Biotech / Development of new drugs
# Record card
153
Description

To the enterprises working in the field of nutrition/nutraceutics and drug development/repositioning, we offer the know-how and state-of-the-art instrumentation of our labs to monitor multiple relevant biological parameters at the cellular level: metabolic activity, vitality, health, but also stress and toxicity. The use of advanced imaging techniques based on fluorescent/bioluminescent probes together with the availability of time-lapse acquisitions, guarantee the cutting-edge analysis of different biological parameters over time.

Thematic areas
Health & Biotech
Health & Biotech / Micro and nanotechnology related to biological sciences
Health & Biotech / Bio-medicals
Health & Biotech / New therapies
Health & Biotech / Diagnostic, Medical imaging & advanced bioimaging
Health & Biotech / Development of new drugs
Health & Biotech / Biosensors
Agrifood
Agrifood / Nutrition & health
Agrifood / Food quality & safety
# Record card
93
Description

Safe, efficient and specific nano-delivery systems are increasingly needed for precision and regenerative medicine and targeted therapies (e.g. anticancer and antimicrobial therapies), as well as for  the cosmetic and nutraceutical sectors’ applications. Despite the appreciable success of synthetic nanovectors, like for example liposomes, their clinical and market application is hampered by some limitations: • large scale production, • low cost production • intrinsic toxicity • limited cellular uptake • limited consumer acceptance.

Thematic areas
Health & Biotech / Micro and nanotechnology related to biological sciences
Materials / Processes of production & treatment of materials
Chemicals & Physics / Micro and nanotechnology related to physical, chemical and exact sciences
Agrifood / Marine resources
Agrifood / Nutrition & health
Health & Biotech / Nanomedicine
Health & Biotech / Development of new drugs
Chemicals & Physics / Subtainable substances and green chemistry
Health & Biotech / Regenerative Medicine