Organotypic models of ovarian cancer are 3D models containing defined extracellular matrices, such as collagen and fibronectin, ovarian cancer cells with specific genetic/molecular characteristics, and one or more cancer-associated stromal cell types (fibroblasts, mesothelial cells, endothelial cells) to mimic specific metastatic niches of ovarian cancer (omentum, peritoneum, interstitial stroma) and the complex interactions within tumor tissues.
Technologies
In this section it is possible to view, also through targeted research, the technologies inserted in the PROMO-TT Database. For further information on the technologies and to contact the CNR Research Teams who developed them, it is necessary to contact the Project Manager (see the references at the bottom of each record card).
Displaying results 1 - 15 of 52
4Ts Game was born in ITD in 2017 to indicate a board game for teacher training, which aims to develop skills in designing collaborative learning activities. The game was originally conceived as a 'tangible' game, consisting of a board and 4 decks of paper cards which contain inputs that guide the teachers/players' design process. Subsequently the game evolved and was developed in its digital version. In this version, developed in Unity and with an underlying knowledge base in Prolog, the game is able to provide feedback to teachers regarding the design/game choices made.
Ageing characterization of Balsamic Vinegar of Modena (BVM) and Traditional Balsamic Vinegar of Modena (TBVM) by the combined use of Nuclear Magnetic Resonance spectroscopy (NMR) and multivariate statistical analysis. Our database allows to differentiate BVM from TBVM samples. Moreover, within BVMs, samples with ageing <3/>3 years can be discriminated and within TBVM, samples with ageing between 12 and 25 years as well as >25 years can be discriminated.
The proposed technology consists of a portable device for monitoring the freshness of fish, based on its smell. The device is based on a gas sensor and pattern recognition software to correlate the sensor signal to the freshness of the food. The technology is designed for its integration into domestic or industrial refrigerators.
Combined use of High-Resolution Nuclear Magnetic Resonance spectroscopy (NMR) and multivariate statistical analysis for the differentiation of PDO Parmigiano Reggiano samples according to ripening and for the differentiation of PDO Parmigiano Reggiano from “Grana type” products available on the market.
B-ME developed the first thermoplastic composite electrode film based on bio-derived and biodegradable polyesters and carbon nano-fibers. It is metal-free, highly electrically conductive and possess good thermo-mechanical properties, a challenging combination of three features in a single product. This is the first-of-its-kind product, as, to the best of our knowledge, no thermoplastic biobased electrode film has been effectively produced and used so far.
The dramatic global health emergency due to the SARS-CoV-2 pandemic requires new diagnostic devices capable of identifying the presence of virus particles in patient biological samples. In this direction, the development of an innovative low-cost test, which provides the result within a few minutes, which is reproducible and which can reveal the direct presence of even a few viral particles, would be of fundamental importance for the monitoring and containment of the pandemic.
The final technology will add polarimetric capability to imaging cameras in the NUV/optical, providing simultaneous measurements of the different polarization states of the light. This will be obtained by the development of an innovative coating based on nanostructured emissive materials sensitive to the polarization of the incident light. A double layer film of two organic systems will be coupled to image detectors so that the two polarization components of the incoming light are converted into two different colors.
The portable device is intended to assess exposure to electromagnetic fields produced by an MRI equipment. The device (dosimeter) allows to improve the analysis and study of the problems related to the exposure of the operators, starting from the technical-scientific aspects related to the exposure, also allowing to create a manual of best practices as well as to improve the professional training of operators.
Digital Eye is an innovative, rapid and high-precision intelligent computer vision system for the non-destructive and contactless evaluation of quality and shelf-life of whole or fresh-cut fruit and vegetables. It integrates advanced vision and artificial intelligence technologies to estimate parameters useful to evaluate the quality of fruit and vegetables, during both the harvesting phase and the cold chain.
The virtual dynamic docking, carried out in the MOLBD3 lab of the Institute of Biophysics, allows the identification of new drugs through the structural information deriving from the study of target proteins, responsible for some human pathologies. In particular, we screen drugs or small molecules (commercial/own libraries) against known protein sites, surface cavities, surfaces of protein-protein interactions (fixed/rigid hotspots) or structural transition states (dynamic hotspots).
Our innovative proposal involves an educational robotics training program, resulting from an experimental research that combines traditional educational approaches with the utilization of robotics. Specifically, the educational robot Thymio, developed by EPFL, serves as a facilitator in the learning process to enhance School Readiness.
The insertion of executable programs within QR codes is a new enabling technology for many application contexts in everyday life. Every time Internet access is unavailable, QR code usage is limited to reading the data it contains without any possibility of interaction.
The proposed technology takes advantages of the huge potentialities of the gellan gum microgels in the preservation of cultural heritage. Microgels are polymeric gels particles with the micro and nanoscale size, whose soft nature is due to the presence of the aqueous solvent inside the particle. For their small size, they can easily diffuse in the environment and penetrate in the porous structure of paper and wood to act as cleaner agent.
VisLab laboratory of IMM possesses a latest generation Raman micro-spectroscope equipped for vibrational measurements with high spatial and spectral resolution, at controlled temperature and in fast-imaging. The apparatus can be used to collect information and chemico-physical maps without the need for sample preparation and alteration, therefore for non-destructive studies and in operating conditions.