Technologies

In this section it is possible to view, also through targeted research, the technologies inserted in the PROMO-TT Database. For further information on the technologies and to contact the CNR Research Teams who developed them, it is necessary to contact the Project Manager (see the references at the bottom of each record card).

Displaying results 1 - 9 of 9

# Record card
161
Description

AIDD is an integrated tool and a radically new way to discovery new drugs for neurodegenerative diseases (Alzheimer’s, Epilepsy, Ageing, etc.).

Thematic areas
Health & Biotech
Health & Biotech / Bio-informatics
Health & Biotech / Smart Devices for Health and Wellness
Health & Biotech / Development of new drugs
Energy and environmental sustainability
Energy and environmental sustainability / Simulation
# Record card
149
Description

Direct quantification of the percentage of arabica in roasted and ground coffee blends of arabica/robusta by High Resolution Nuclear Magnetic Resonance spectroscopy (NMR), in solution and multivariate statistical analysis. Particularly, the metabolites content present in water extracts of coffee is analyzed and compared with NMR data of our database.

Thematic areas
Agrifood
Agrifood / Food quality & safety
Agrifood / Nutrition & health
# Record card
25
Description

The Biocrystal Facility, a large multidisciplinary laboratory established at the Institute of Molecular Biology and Pathology (IBPM) of CNR, in collaboration with the Biochemistry Department of Sapienza University aims at supporting the italian scientists and the pharmaceutical companies in the research to find new drug and vaccine against the endemic and epidemic diseases through structure-based drug design.

Thematic areas
Health & Biotech / Bio-informatics
Health & Biotech / Nanomedicine
Health & Biotech / Development of new drugs
# Record card
150
Description

The virtual dynamic docking, carried out in the MOLBD3 lab of the Institute of Biophysics, allows the identification of new drugs through the structural information deriving from the study of target proteins, responsible for some human pathologies. In particular, we screen drugs or small molecules (commercial/own libraries) against known protein sites, surface cavities, surfaces of protein-protein interactions (fixed/rigid hotspots) or structural transition states (dynamic hotspots).

Thematic areas
Health & Biotech
Health & Biotech / Development of new drugs
Health & Biotech / Bio-medicals
Health & Biotech / Bio-informatics
# Record card
36
Description

We developed a procedure aimed at simultaneously treating thousands of C.elegans model organisms, from eggs to old adult, in liquid, in 96- or 384-well plates. This procedure can be used to perform drug and toxicological screening of millions of compounds, in very small volumes and on millions of animals. Thanks to easy handling, semi-automatic analysis can be performed using plate readers or High Content Screening instruments.

Thematic areas
Agrifood / Agriculture
Agrifood / Nutrition & health
Agrifood / Food quality & safety
# Record card
29
Description

The aim of the research group is the creation of 3D models (microorgan/ organoids) constructed using samples obtained from patients, both biopsy samples and samples collected with non-invasive techniques (exhaled breath condensate, induced sputum, blood samples).

Thematic areas
Health & Biotech / New therapies
Health & Biotech / Smart Devices for Health and Wellness
Health & Biotech / Medical Device
# Record card
260
Description
Thematic areas
Agrifood
Agrifood / Nutrition & health
Agrifood / Food quality & safety
Health & Biotech
Health & Biotech / Development of new drugs
Additive and advanced industrial manufacturing
Health & Biotech / Biosensors
Health & Biotech / Bio-medicals
Chemicals & Physics
Additive and advanced industrial manufacturing / Packaging
Chemicals & Physics / Agro chemicals
Additive and advanced industrial manufacturing / Additive manufacturing processes and materials
Health & Biotech / Diagnostic kits
Chemicals & Physics / Colours & dyes
Chemicals & Physics / Plastics & rubber
Chemicals & Physics / Detergents & cleaning technologies
# Record card
40
Description

Recently, it has been demonstrated that Raman spectroscopy can play a fundamental role in assisting the work of the anatomopathologist by allowing classification of oncological samples with practically 100% accuracy in oncological diagnosis.

Thematic areas
Health & Biotech / Micro and nanotechnology related to biological sciences
Health & Biotech / Nanomedicine
Health & Biotech / Diagnostic, Medical imaging & advanced bioimaging
Chemicals & Physics / Micro and nanotechnology related to physical, chemical and exact sciences
ICT & Electronics / Artificial Intelligence
# Record card
67
Description

This is a high-throughput sequencing based method to map euchromatin and heterochromatin accessibility. The method is based on the sequential extraction of distinct nuclear fractions containing: soluble proteins (S1 fraction); the surnatant obtained after DNase treatment (S2 fraction); DNase-resistant chromatin extracted with high salt buffer (S3 fraction); and the most condensed and insoluble portion of chromatin, extracted with urea buffer that solubilizes the remaining proteins and membranes (S4 fraction).

Thematic areas
Health & Biotech / Bio-medicals
Health & Biotech / Diagnostic kits