Technologies

The proposed technology deals with the development of active SERS (Surface Enhanced Raman Scattering) substrates ad hoc designed for diagnostics of cultural heritage. The substrates are prepared starting from common commercial 'polishing film' sheets (lapping optical fibers) showing an intrinsic roughness (48- 1000 nm) that favors the SERS effect. A pattern of silver or gold nanoparticles are deposited on these films through Pulsed Laser Deposition (PLD).

We developed an hybrid organic-inorganic composite consisting of a 2D perovskite and a copolymer. At room temperature the composite is highly transparent in the visible region with transmittance > 90%. At higher temperatures, the movement of the polymer chains releases the precursors, allowing the perovskite formation, which results in a colored film. The color changes according to the ‘n’ value of the PVK. PVK with n=1 starts coloring at 70°C, achieving a ∆T_max = 91.5% at 510 nm.

The invention is a synthetic method to prepare colloidal nanomaterials of V-VI-VII semiconductors that do not contain toxic elements. This is the first method for the synthesis of mixed anion nanomaterials without toxic elements at large, which permitted to obtain, among others, bismuth chalcohalide nanocrystals that are arguably considered as one of main candidates to be the next big thing for light energy conversion.

Recently, it has been demonstrated that Raman spectroscopy can play a fundamental role in assisting the work of the anatomopathologist by allowing classification of oncological samples with practically 100% accuracy in oncological diagnosis.

To the enterprises working in the field of nutrition/nutraceutics and drug development/repositioning, we offer the know-how and state-of-the-art instrumentation of our labs to monitor multiple relevant biological parameters at the cellular level: metabolic activity, vitality, health, but also stress and toxicity. The use of advanced imaging techniques based on fluorescent/bioluminescent probes together with the availability of time-lapse acquisitions, guarantee the cutting-edge analysis of different biological parameters over time.

The invention consists in a special regulation method of the horizontal axes of operating and rubbing wheels of a centerless grinding machine coupled with an opportune blade profile, allowing a continuous regulation of blade rest angle (angle between tangent to blade profile at the contact point with the work piece and the horizon, denoted by γ) and workpiece height (denoted by hw), without requiring blade substitution and/or manual regulations.

Grape pomace, a by-product of wine-making, is rich in polyphenols, metals, organic acids and can become a functional ingredient in food and beverage. The stabilisation of the pomace has been optimised to preserve the anti-inflammatory and antioxidant properties of the molecules present. Isolated grape skins have been reused in purity or in blends with other plant components as a base for: 1) herbal teas, 2) ready-to-drink functional beverages, 3) freeze-dried products.

The invention concerns an apparatus for measuring the three-dimensional (3-D) sea surface elevation from moving and floating platforms. In particular, the invention consists of two or more synchronized digital video-cameras that frame, from distinct and remote points of view, a common portion of the sea surface. A triangulation process makes it possible to obtain a three-dimensional reconstruction of the sea surface from these images. The invention is particularly suitable for measuring sea waves.

The substitution of fossil derived monomers in thermosetting resins is a very important point to look at to face environmental impact issues related with the use of traditional resins. The research group set up a protocol for the preparation of thermosetting resins starting from vegetable oils with different composition to substitute the petroleum-based monomers. The materials obtained in this way have a bio-based carbon content higher than 80%.

Our team can develop low-cost ultra-flexible sensors integrated on plastic substrate for volatile organic compounds (VOCs) and gas detection. These devices combine scalable fabrication technologies, implementing active materials such as nanostructured metal oxides or stack of nanostructures decorated with metal nanoparticles, thus enabling a high sensitivity (in the range of hundreds of ppb). These devices can be applied to numerous industrial and commercial sectors and they can be embedded in systems that are more sophisticated.

IMM has developed tactile sensors for the detection of objects and surface and for the handling of objects with humanoid robots (e-skin). These devices can be integrated on ultra-flexible and high conformable substrates and they can be used for multiple applications: 1) for a correct interaction with objects distributed in complex environment; 2) for a safe short-range interaction between humanoid robot and humans; 3) for fabricating smart wearables for the detection of biometric parameters (e.g. heartbeat); 4) for remotely control rovers with wearable gadgets.

Safe, efficient and specific nano-delivery systems are increasingly needed for precision and regenerative medicine and targeted therapies (e.g. anticancer and antimicrobial therapies), as well as for  the cosmetic and nutraceutical sectors’ applications. Despite the appreciable success of synthetic nanovectors, like for example liposomes, their clinical and market application is hampered by some limitations: • large scale production, • low cost production • intrinsic toxicity • limited cellular uptake • limited consumer acceptance.

Environmental monitoring is a rapidly growing field, both in academia and industry. The use of wearables for environmental monitoring is a promising technique, as it allows data to be collected continuously and comprehensively. The main problem with using wearables for environmental monitoring is the size and weight of the system, as well as the high degree of specialization required to develop a fully functional device.

X-ray imaging techniques can work in i) "full-field mode" in which the object to study (or part of it) is completely illuminated by the X-ray beam; ii) "scanning mode" in which an X-ray beam, focused through an opportune optics, illuminates in succession contiguous areas of the sample under examination, and the transmitted wave is measured by a detector placed at a proper distance from it. One of these X-ray scanning microscopes is available at the facility (X-ray MicroImaging, XMIL@b) of the Institute of Crystallography (CNR-Bari).