Organotypic models of ovarian cancer are 3D models containing defined extracellular matrices, such as collagen and fibronectin, ovarian cancer cells with specific genetic/molecular characteristics, and one or more cancer-associated stromal cell types (fibroblasts, mesothelial cells, endothelial cells) to mimic specific metastatic niches of ovarian cancer (omentum, peritoneum, interstitial stroma) and the complex interactions within tumor tissues.
Technologies
In this section it is possible to view, also through targeted research, the technologies inserted in the PROMO-TT Database. For further information on the technologies and to contact the CNR Research Teams who developed them, it is necessary to contact the Project Manager (see the references at the bottom of each record card).
Displaying results 1 - 15 of 70
4Ts Game was born in ITD in 2017 to indicate a board game for teacher training, which aims to develop skills in designing collaborative learning activities. The game was originally conceived as a 'tangible' game, consisting of a board and 4 decks of paper cards which contain inputs that guide the teachers/players' design process. Subsequently the game evolved and was developed in its digital version. In this version, developed in Unity and with an underlying knowledge base in Prolog, the game is able to provide feedback to teachers regarding the design/game choices made.
A biosensor based on magnetic microspheres functionalized with a DNA-aptamer was developed for the specific biomonitoring of biological contaminants (mycotoxins) in urine.
The technology for organic thin film transistors (OTFTs) is suitable for large area electronics, disposable electronics and "Internet of Things" applications. Circuits employing OTFTs can be realized by using very cheap printing technologies. The electrical behavior of these devices is essentially different from the behavior of silicon MOSFETs and, in order to enable circuit design, compact models specific for OTFTs are needed.
The presented technology is an electrical compact model for OTFTs that:
The Proof-of-Concept A.L.I.C.E. or "Actuators based on Light sensitive CompositE" aims at the development of innovative materials through 3D/4D printing processes and uses them as actuators in the fields of photovoltaics, concentrated solar power, thermodynamic solar, and other applications such as optical deflectors, optical microvalves, and optical switches.
Ageing characterization of Balsamic Vinegar of Modena (BVM) and Traditional Balsamic Vinegar of Modena (TBVM) by the combined use of Nuclear Magnetic Resonance spectroscopy (NMR) and multivariate statistical analysis. Our database allows to differentiate BVM from TBVM samples. Moreover, within BVMs, samples with ageing <3/>3 years can be discriminated and within TBVM, samples with ageing between 12 and 25 years as well as >25 years can be discriminated.
AIDD is an integrated tool and a radically new way to discovery new drugs for neurodegenerative diseases (Alzheimer’s, Epilepsy, Ageing, etc.).
Aptamers, short structured single-stranded oligonucleotides binding at high affinity to a given target protein, are selected from large combinatorial libraries through repeated cycles of incubation of the library with the target, recovery and amplification of target-bound oligonucleotides (SELEX technology, Systematic Evolution of Ligands by EXponential enrichment). SELEX can be applied to select aptamers against a known target protein or against a specific cell phenotype, without any prior knowledge of the specific target, leading to new biomarkers discovery.
Combined use of High-Resolution Nuclear Magnetic Resonance spectroscopy (NMR) and multivariate statistical analysis for the differentiation of PDO Parmigiano Reggiano samples according to ripening and for the differentiation of PDO Parmigiano Reggiano from “Grana type” products available on the market.
The present invention relates to the biomedical sector of the treatment of lung diseases and related symptoms. In particular, the present invention provides compositions and methods based on the use of selected polymeric biomaterials, in combination with stem cells and/or their secretome, capable of synergistically improving the development, regeneration and repair of chronic lung injuries and related symptoms.
A virtuous multi-step biorefinery platform to convert urban biowaste into valuable molecules, not disregarding renewable energy and digestate production. The strategy is based on the integration of a thermal pretreatment capable of significantly increasing the fraction of fermentable organic carbon, in order to furthermore change the status of the feedstock to become more suitable for production of a) high-value bio-based molecules, b) biomethane and c) hygienized digestate to be recycled as biofertilizer.
Nowadays, to properly design and develop advanced materials capable to preserve for long times their performance under aggressive environments such as power generation plants, renewables, nuclear reactors and electronics of new generation, transport on ground and on space, aeronautics, catalysis, biomedical implants, the optimization of metallurgical processes involved is crucial.
CNR-ISTEC develops geopolymer composites for thermostructural applications, such as: self-supporting cavities; thermal and acoustic insulation; thermal and fire barriers; high temperature coatings and damping; molds and cores for foundry; foams and refractory linings. Geopolymers are chemically bonded materials at T <300 ° C. Being inorganic polymers without water in the structure, they tolerate high temperatures: they are incombustible, do not emit gas or fumes and do not explode.
Digital Eye is an innovative, rapid and high-precision intelligent computer vision system for the non-destructive and contactless evaluation of quality and shelf-life of whole or fresh-cut fruit and vegetables. It integrates advanced vision and artificial intelligence technologies to estimate parameters useful to evaluate the quality of fruit and vegetables, during both the harvesting phase and the cold chain.
Molecular doping (MD) is a doping method based on the use of liquid solutions. The dopant precursor is in liquid form and the material to be doped is immersed in the solution. During the immersion process, the molecule containing the dopant atom is deposited on the surface of the material forming a self-assembled monolayer, that is, ordered and compact. Through a subsequent heat treatment, the molecule decomposes and the dopant diffuses.