Plants can compete favorably with traditional expression systems (mammalian cells, yeasts or bacteria) to produce recombinant proteins/peptides of pharmaceutical/industrial/agrifood interest. This technology names “Plant Molecular Farming”. The CNR-IBBA research team offers the study of new strategies for the expression and optimization of recombinant proteins/peptides in plant-based systems (plant tissues, transgenic plants, plant cell culture). Our pipeline is based on the following modules:
- Design of possible strategies to increase the yield of recombinant protein/peptide of interest in plant-based systems;
- Testing of different strategies by transient expression in plant tissues;
- Production of the prototype plant (or plant cell line) using the best strategy;
- Molecular and functional analysis (post-translational modifications, localization, etc.) of protein/peptide of interest produced in the prototype plant.
Plants can compete favorably with traditional expression systems (mammalian cells, yeasts or bacteria) to produce recombinant proteins/peptides of pharmaceutical/industrial/agrifood interest. This technology names “Plant Molecular Farming”. The CNR-IBBA research team offers the study of new strategies for the expression and optimization of recombinant proteins/peptides in plant-based systems (plant tissues, transgenic plants, plant cell culture). Our pipeline is based on the following modules: • Design of possible strategies to increase the yield of recombinant protein/peptide of interest in plant-based systems • Testing of different strategies by transient expression in plant tissues • Production of the prototype plant (or plant cell line) using the best strategy • Molecular and functional analysis (post-translational modifications, localization, etc.) of protein/peptide of interest produced in the prototype plant.