Technologies

A biosensor based on magnetic microspheres functionalized with a DNA-aptamer was developed for the specific biomonitoring of biological contaminants (mycotoxins) in urine.

The proposed technology is based on the micro-fabrication of electrodes in order to generate surface acoustic waves (SAW) with well-defined frequencies, on piezoelectric substrates. The operating principle of a surface acoustic wave sensor is linked to the variation of the characteristics of the acoustic wave that propagates on the device (e.g. wave velocity on the substrate, etc.) caused by the interaction with the environment (e.g. interaction of an analyte on the surface of the device, deformation of the substrate, etc.).

Digital Eye is an innovative, rapid and high-precision intelligent computer vision system for the non-destructive and contactless evaluation of quality and shelf-life of whole or fresh-cut fruit and vegetables. It integrates advanced vision and artificial intelligence technologies to estimate parameters useful to evaluate the quality of fruit and vegetables, during both the harvesting phase and the cold chain.

Molecular doping (MD) is a doping method based on the use of liquid solutions. The dopant precursor is in liquid form and the material to be doped is immersed in the solution. During the immersion process, the molecule containing the dopant atom is deposited on the surface of the material forming a self-assembled monolayer, that is, ordered and compact. Through a subsequent heat treatment, the molecule decomposes and the dopant diffuses.

Anthocyanins are antioxidant polyphenolic pigments produced by plants that are widely used in the food, cosmetic and pharmaceutical industries. The technology allows to obtain in a short time potato cell lines in which the production of highly acetylated and highly complex anthocyanins is increased in addition to other antioxidant polyphenolic compounds. The obtained cellular lines have a high production efficiency, comparable to the extraction of berries, but with the advantage of having an on-demand production which is not limited to seasonality.

NIRS is a non-invasive technique for the human brain cortex imaging based on the measurement of the NIR light emitted by suitable optical sources placed on the patient head and backdiffused to the surface after passing through the brain tissues. NIRS monitors the percentage of oxygenated and reduced hemoglobin  in the blood, and it allows the real time functional imaging of the brain cortex also in tomographic mode (Diffuse Optical Tomography - DOT).

Uniform coverage with porous layers over extended surfaces is beneficial for many purposes. Depending on the nature/composition, thickness and interfaces of the layer, this kind of special coverage can assure pivotal properties such as transparency, bendability, high surface reactivity, intermixing capability. In the long list of desired porous materials, transparent oxides find application in the fields of Photovoltaics, Sensing, Photocatalysis, Water Purification and Splitting, Lithium Batteries and many more.

We propose a compact innovative spectroscopy system operating in the UV range. In the actual version, designed for gas, it exhibits: an aluminium tubular optical chamber (length can be adjusted; currently is 20 cm); a cheap commercial UV LED; a SiC visible blind UV detector designed and manufactured at the CNR-IMM facilities. The team developed also the electronic chain for wireless remote real time read out; while able to deal with pA current levels, it uses very cheap components and construction technology.

The procedure enables the fabrication of nanocomposite membranes filled with suitable amounts of exfoliated bidimensional crystals. These are obtained with an advanced wet-jet milling technique, which provides desired thickness and lateral size of nanofillers through the pulverization and colloidal homogenization of bulk nanomaterials. The bidimensional crystals are dispersed in fluids and suitably delivered inside polymeric matrixes exhibiting a singular morphology.

The systems simulate, with high reproducibility, the conditions that occur in the different compartments of the gastrointestinal tracts and are promising to accurately mimic the digestive process, with the possibility to evaluate bioaccessibility and bioavailability. Moreover, the systems permit to study the synergic and reciprocal effects between the bioactive compounds characteristic of food and intestinal microbiota.

Plants can compete favorably with traditional expression systems (mammalian cells, yeasts or bacteria) to produce recombinant proteins/peptides of pharmaceutical/industrial/agrifood interest. This technology names “Plant Molecular Farming”. The CNR-IBBA research team offers the study of new strategies for the expression and optimization of recombinant proteins/peptides in plant-based systems (plant tissues, transgenic plants, plant cell culture). Our pipeline is based on the following modules:

The platform allows acquisition of data from commercial and custom sensors. By now, the system has been embedded in a wearable wristband where elastomeric based strain gauge have been integrated to detect fine hand/wrist/arm movements. The platform integrates inertial sensors (accelerometers, gyroscopes) to acquire more details about the subject movements. A sensor-fusion algorithm enables advanced movement recognition (gesture, 3D orientation). A machine-learning algorithm is in development to increase the performance of the platform.

The environment as well as the food production provide a number of both natural and synthetic compounds whose effects on human being as an organism have not yet been determined nor investigated.

The proposed technology deals with the development of active SERS (Surface Enhanced Raman Scattering) substrates ad hoc designed for diagnostics of cultural heritage. The substrates are prepared starting from common commercial 'polishing film' sheets (lapping optical fibers) showing an intrinsic roughness (48- 1000 nm) that favors the SERS effect. A pattern of silver or gold nanoparticles are deposited on these films through Pulsed Laser Deposition (PLD).

Wine is one of the economically most important beverages and may be subject to fraud and mislabelling, although that there are specific and strict rules protecting its authenticity in Europe. Single Nucleotide Polymorphisms (SNPs), recently identified and characterized thanks to advances in genomics, are considered the newest type of molecular marker for grapevine identification.