Technologies

In this section it is possible to view, also through targeted research, the technologies inserted in the PROMO-TT Database. For further information on the technologies and to contact the CNR Research Teams who developed them, it is necessary to contact the Project Manager (see the references at the bottom of each record card).

Displaying results 46 - 58 of 58

# Record card
174
Description

Plants can compete favorably with traditional expression systems (mammalian cells, yeasts or bacteria) to produce recombinant proteins/peptides of pharmaceutical/industrial/agrifood interest. This technology names “Plant Molecular Farming”. The CNR-IBBA research team offers the study of new strategies for the expression and optimization of recombinant proteins/peptides in plant-based systems (plant tissues, transgenic plants, plant cell culture). Our pipeline is based on the following modules:

Thematic areas
Agrifood
Agrifood / Nutrition & health
Health & Biotech
Health & Biotech / Development of new drugs
Health & Biotech / Regenerative Medicine
# Record card
140
Description

The technology refers to an innovative plasma (ionized gas) source operating at atmospheric pressure and low electric power levels. A cold plasma is produced, characterized by an ion temperature significantly lower than the electron temperature. Partial ionization of a Helium flux is induced by a time-varying electric field in between two parallel grids, both perpendicular to the flux itself.

Thematic areas
Health & Biotech
Health & Biotech / Bio-medicals
Health & Biotech / Care, Hygiene, Cosmetics
Health & Biotech / New therapies
Health & Biotech / Medical Device
Chemicals & Physics
Chemicals & Physics / Cold Plasmas
# Record card
260
Description
Thematic areas
Agrifood
Agrifood / Nutrition & health
Agrifood / Food quality & safety
Health & Biotech
Health & Biotech / Development of new drugs
Additive and advanced industrial manufacturing
Health & Biotech / Biosensors
Health & Biotech / Bio-medicals
Chemicals & Physics
Additive and advanced industrial manufacturing / Packaging
Chemicals & Physics / Agro chemicals
Additive and advanced industrial manufacturing / Additive manufacturing processes and materials
Health & Biotech / Diagnostic kits
Chemicals & Physics / Colours & dyes
Chemicals & Physics / Plastics & rubber
Chemicals & Physics / Detergents & cleaning technologies
# Record card
38
Description

The Q-PLL is a nonlinear circuit which can maintain a locked state when forced by two incommensurate frequencies.

The locked state is a third frequency parametrically selected among those prescribed by the theory of three-frequency resonances in dynamical systems.

In particular, the locked frequency forms a three-frequency resonance with the frequencies of the quasi- periodic input and is closely related to the pitch perception of complex sound in humans.

Thematic areas
Materials / Properties of materials, corrosion, degradation
ICT & Electronics / Sensor/multi-sensor technology, instrumentation
ICT & Electronics / Optics & Acoustic
ICT & Electronics / Robotics and control systems
Health & Biotech / Medical Device
Health & Biotech / Micro and nanotechnology related to biological sciences
Health & Biotech / Bio-medicals
ICT & Electronics / Electronics and microelectronics
ICT & Electronics / Information processing, information system, workflow management
ICT & Electronics / IT and Telematics applications
ICT & Electronics / Multimedia
ICT & Electronics / Telecommunications
# Record card
153
Description

To the enterprises working in the field of nutrition/nutraceutics and drug development/repositioning, we offer the know-how and state-of-the-art instrumentation of our labs to monitor multiple relevant biological parameters at the cellular level: metabolic activity, vitality, health, but also stress and toxicity. The use of advanced imaging techniques based on fluorescent/bioluminescent probes together with the availability of time-lapse acquisitions, guarantee the cutting-edge analysis of different biological parameters over time.

Thematic areas
Health & Biotech
Health & Biotech / Micro and nanotechnology related to biological sciences
Health & Biotech / Bio-medicals
Health & Biotech / New therapies
Health & Biotech / Diagnostic, Medical imaging & advanced bioimaging
Health & Biotech / Development of new drugs
Health & Biotech / Biosensors
Agrifood
Agrifood / Nutrition & health
Agrifood / Food quality & safety
# Record card
152
Description

The proposed system is based on a high-resolution electrocardiograph in which the electrodes are positioned on maternal abdomen. The acquired signals are processed using a completely unsupervised software for fetal ECG extraction based on independent component analysis, maternal ECG canceling and a quality index optimization. The electrocardiograph is constituted by a light-weight and light-dimension portable unit, which acquires the signals and transmit them to a computer where the analysis software runs.

Thematic areas
Health & Biotech
Health & Biotech / Bio-medicals
Health & Biotech / Smart Devices for Health and Wellness
Health & Biotech / Diagnostic, Medical imaging & advanced bioimaging
# Record card
67
Description

This is a high-throughput sequencing based method to map euchromatin and heterochromatin accessibility. The method is based on the sequential extraction of distinct nuclear fractions containing: soluble proteins (S1 fraction); the surnatant obtained after DNase treatment (S2 fraction); DNase-resistant chromatin extracted with high salt buffer (S3 fraction); and the most condensed and insoluble portion of chromatin, extracted with urea buffer that solubilizes the remaining proteins and membranes (S4 fraction).

Thematic areas
Health & Biotech / Bio-medicals
Health & Biotech / Diagnostic kits
# Record card
87
Description

SITODIET is an innovative software that supports a translational approach to health’s state. It integrates various sources of physiological, behavioral, and psychological data to reduce the risks associated with the onset of lifestyle-related diseases (primary prevention), to support health professionals in early diagnosis (secondary prevention) or to manage the personalized therapy’s patient (tertiary prevention). SITODIETcollects data automatically, through actigraphy tools, as wristband or smartwatch, or manually

Thematic areas
ICT & Electronics / Big Data
Agrifood / Nutrition & health
Health & Biotech / Smart Devices for Health and Wellness
ICT & Electronics / Artificial Intelligence
ICT & Electronics / IT and Telematics applications
# Record card
51
Description

Environmental contamination is a prominent topic. Where the exposure to contaminants such as heavy metals (HMs) or polycyclic aromatic hydrocarbons (PAHs) is greater, the incidence of chronic degenerative diseases, such as oncologic, is increased. Scientific evidence reports that some phytochemicals are able to interact with HMs and PAHs by interfering with their cellular metabolism, inhibiting their cytotoxic mechanisms or helping to reduce tissue concentrations.

Thematic areas
Agrifood / Nutrition & health
# Record card
162
Description

Grape pomace, a by-product of wine-making, is rich in polyphenols, metals, organic acids and can become a functional ingredient in food and beverage. The stabilisation of the pomace has been optimised to preserve the anti-inflammatory and antioxidant properties of the molecules present. Isolated grape skins have been reused in purity or in blends with other plant components as a base for: 1) herbal teas, 2) ready-to-drink functional beverages, 3) freeze-dried products.

Thematic areas
Agrifood
Agrifood / Nutrition & health
Bioeconomy
Energy and environmental sustainability
Energy and environmental sustainability / Renewable sources
# Record card
138
Description

We present a technology for the multiscale isolation (analytical-laboratory-production) of Extracellular Vesicles (VE), which overcomes the limitations of the currently available methods. As opposed to traditional "affinity-based" systems that exploit antibodies, our technology represents a radical paradigm shift in the development of affinity probes for vesicles, i.e.

Thematic areas
Health & Biotech
Health & Biotech / Smart Devices for Health and Wellness
Health & Biotech / Nanomedicine
Health & Biotech / Diagnostic, Medical imaging & advanced bioimaging
Health & Biotech / Regenerative Medicine
Health & Biotech / Care, Hygiene, Cosmetics
Health & Biotech / Biosensors
Health & Biotech / Micro and nanotechnology related to biological sciences
Health & Biotech / Bio-medicals
Health & Biotech / Diagnostic kits
Chemicals & Physics
Chemicals & Physics / Separation technologies
# Record card
21
Description

Our treatment demonstrated the ability to kill metastatic human melanoma cells, for which there are very few effective therapeutic approaches. Use of a specific Essential Oil (EO) to inhibit the replication of human metastatic melanoma cells. This EO can be used both for direct application to the skin, and administered by mouth to reach both primary and metastatic melanomas.

Thematic areas
Agrifood / Nutrition & health
Health & Biotech / Regenerative Medicine
Health & Biotech / New therapies
# Record card
93
Description

Safe, efficient and specific nano-delivery systems are increasingly needed for precision and regenerative medicine and targeted therapies (e.g. anticancer and antimicrobial therapies), as well as for  the cosmetic and nutraceutical sectors’ applications. Despite the appreciable success of synthetic nanovectors, like for example liposomes, their clinical and market application is hampered by some limitations: • large scale production, • low cost production • intrinsic toxicity • limited cellular uptake • limited consumer acceptance.

Thematic areas
Health & Biotech / Micro and nanotechnology related to biological sciences
Materials / Processes of production & treatment of materials
Chemicals & Physics / Micro and nanotechnology related to physical, chemical and exact sciences
Agrifood / Marine resources
Agrifood / Nutrition & health
Health & Biotech / Nanomedicine
Health & Biotech / Development of new drugs
Chemicals & Physics / Subtainable substances and green chemistry
Health & Biotech / Regenerative Medicine